BTBD3 - BTB domain containing 3 Gene

Homo sapiens

Also known as dJ742J24.1

Gene ID: 22903 | Gene type: protein coding

About BTBD3

Cytogenetic location: 20p12.2 Genomic coordinates (GRCh38): 20:11,890,817-11,926,595 (from NCBI)

This gene has 15 transcripts (splice variants), 217 orthologues and 11 paralogues. Ubiquitous expression in placenta (RPKM 23.1), brain (RPKM 20.6) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in cerebral cortex development and dendrite morphogenesis. Predicted to be located in nucleus. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

BTBD3 Products(13)

mRNA	Protein	Name
NM_001282550.3	NP_001269479.1	BTB/POZ domain-containing protein 3 isoform b
NM_001282551.2	NP_001269480.1	BTB/POZ domain-containing protein 3 isoform b
NM_001282552.3	NP_001269481.1	BTB/POZ domain-containing protein 3 isoform c
NM_001282554.2	NP_001269483.1	BTB/POZ domain-containing protein 3 isoform c
NM_001395003.1	NP_001381932.1	BTB/POZ domain-containing protein 3 isoform b
NM_001395004.1	NP_001381933.1	BTB/POZ domain-containing protein 3 isoform c
NM_001395005.1	NP_001381934.1	BTB/POZ domain-containing protein 3 isoform a
NM_001395006.1	NP_001381935.1	BTB/POZ domain-containing protein 3 isoform a
NM_001395007.1	NP_001381936.1	BTB/POZ domain-containing protein 3 isoform b
NM_001395008.1	NP_001381937.1	BTB/POZ domain-containing protein 3 isoform c
NM_001395009.1	NP_001381938.1	BTB/POZ domain-containing protein 3 isoform b
NM_014962.4	NP_055777.1	BTB/POZ domain-containing protein 3 isoform a
NM_181443.4	NP_852108.3	BTB/POZ domain-containing protein 3 isoform b

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BTBD3 Protein Structure

BTB

BACK

PHR

0
100
200
300
400
522 a.a.

Protein Preferred Names

Protein Names

BTB/POZ domain-containing protein 3

BTB (POZ) domain containing 3

BTBD3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	BTBD3	Q9Y2F9	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	32296183
Intra	BTBD3	Q9Y2F9	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	BTBD6	Homo sapiens	Q96KE9-2	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	BTBD6	Homo sapiens	Q96KE9-2	Y2H Array	32296183
Intra	BTBD3	Q9Y2F9	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	BTBD3	Q9Y2F9	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	BTBD3	Q9Y2F9	BTBD3	Homo sapiens	Q9Y2F9	Y2H Array	32296183
Intra	BTBD3	Q9Y2F9	BTBD3	Homo sapiens	Q9Y2F9	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	SUMO1	Homo sapiens	P63165	Y2H Prey Pooling	32296183
Intra	BTBD3	Q9Y2F9	BTBD3	Homo sapiens	Q9Y2F9	Validated Y2H	32296183
Intra	BTBD3	Q9Y2F9	SUMO1	Homo sapiens	P63165	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Trichotillomania

TTM	Hair-Pulling Syndrome
Compulsive Hair Plucking	Hair Pulling Disorder

Body Dysmorphic Disorder

Dysmorphophobia	Body Dysmorphia
Dysmorphic Syndrome	Body Dysmorphic Disorders

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01656	BTBD3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	BTBD3	VGNC	VGNC:38552
Rattus norvegicus	BTBD3	RGD	RGD:1311623
Macaca mulatta	BTBD3	VGNC	VGNC:84547
Felis catus	BTBD3	VGNC	VGNC:60200
Bos taurus	BTBD3	VGNC	VGNC:26590
Mus musculus	BTBD3	MGD	MGI:2385155

Name
Email *

	Sorry, but the email address you supplied was invalid.