ZC3H13 - zinc finger CCCH-type containing 13 Gene

Homo sapiens

Also known as Xio; KIAA0853

Gene ID: 23091 | Gene type: protein coding

About ZC3H13

Cytogenetic location: 13q14.13 Genomic coordinates (GRCh38): 13:45,954,465-46,052,746 (from NCBI)

This gene has 6 transcripts (splice variants) and 158 orthologues. Ubiquitous expression in brain (RPKM 10.7), thyroid (RPKM 9.2) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mRNA methylation. Located in nuclear speck. Part of RNA N6-methyladenosine methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H13 Products(15)

mRNA	Protein	Name
NM_001076788.2	NP_001070256.1	zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330564.2	NP_001317493.1	zinc finger CCCH domain-containing protein 13 isoform 1
NM_001330565.2	NP_001317494.1	zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330566.2	NP_001317495.1	zinc finger CCCH domain-containing protein 13 isoform 2
NM_001330567.2	NP_001317496.1	zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382206.1	NP_001369135.1	zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382207.1	NP_001369136.1	zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382208.1	NP_001369137.1	zinc finger CCCH domain-containing protein 13 isoform 1
NM_001382209.1	NP_001369138.1	zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382210.1	NP_001369139.1	zinc finger CCCH domain-containing protein 13 isoform 2
NM_001382211.1	NP_001369140.1	zinc finger CCCH domain-containing protein 13 isoform 4
NM_001382212.1	NP_001369141.1	zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382213.1	NP_001369142.1	zinc finger CCCH domain-containing protein 13 isoform 5
NM_001382214.1	NP_001369143.1	zinc finger CCCH domain-containing protein 13 isoform 6
NM_015070.6	NP_055885.3	zinc finger CCCH domain-containing protein 13 isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20195357	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mRNA processing	IMP IMP: Inferred from mutant phenotype	29507755	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of RNA N6-methyladenosine methyltransferase complex	IDA IDA: Inferred from direct assay	29507755	GOA
part of RNA N6-methyladenosine methyltransferase complex	IPI IPI: Inferred from physical interaction	29507755	GOA
located in nuclear speck	IDA IDA: Inferred from direct assay	24100041	GOA
located in nucleoplasm	IDA IDA: Inferred from direct assay	24100041	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H13 Protein Structure

zf-CCCH

0
300
600
900
1200
1500
1668 a.a.

Protein Preferred Names

Protein Names

zinc finger CCCH domain-containing protein 13

ZC3H13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ZC3H13	Q5T200	SCHIP1	Homo sapiens	P0DPB3	Display Tech	20195357

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Uterine Corpus Endometrial Carcinoma

Wilms Tumor 1

Nephroblastoma	Wilms Tumor
WT1	Wilms' Tumor
Bilateral Wilms Tumor	Wilms Tumor, Type 1
Wilms Tumor, Somatic	Adult Nephroblastoma
Wt1 Disorder	Renal Embryonic Tumor
Adult Kidney Wilms Tumor	Childhood Kidney Wilms Tumor
Nonanaplastic Kidney Wilms Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15988	ZC3H13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZC3H13	VGNC	VGNC:37101
Rattus norvegicus	ZC3H13	RGD	RGD:1307729
Canis familiaris	ZC3H13	VGNC	VGNC:48554
Macaca mulatta	ZC3H13	VGNC	VGNC:79248
Felis catus	ZC3H13	VGNC	VGNC:67183
Mus musculus	ZC3H13	MGD	MGI:1914552

Name
Email *

	Sorry, but the email address you supplied was invalid.