2. Gene
  3. Fgl1 - fibrinogen-like protein 1 Gene

Fgl1 - fibrinogen-like protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mfire1

Gene ID: 234199 | Gene type: protein coding

About Fgl1

Summary

Predicted to enable signaling receptor binding activity. Involved in negative regulation of T cell activation and regulation of immune response. Acts upstream of or within several processes, including adipose tissue development; Cholesterol metabolic process; and response to stilbenoid. Located in extracellular region. Orthologous to human FGL1 (fibrinogen like 1). [provided by Alliance of Genome Resources, Apr 2022]

Fgl1 Products(1)

mRNA Protein Name
NM_145594.2 NP_663569.2 fibrinogen-like protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
30580966 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30580966 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adipose tissue development IMP
IMP: Inferred from mutant phenotype
23483972 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: Inferred from mutant phenotype
23483972 MGI
involved in negative regulation of T cell activation IDA
IDA: Inferred from direct assay
30580966 MGI
acts upstream of or within regulation of glucose metabolic process IMP
IMP: Inferred from mutant phenotype
23483972 MGI
involved in regulation of immune response IDA
IDA: Inferred from direct assay
30580966 MGI
involved in response to stilbenoid IEP
IEP: Inferred from expression pattern
17086191 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
30580966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibrinogen-like protein 1

MFIRE-1

fibrinogen-related protein 1

liver fibrinogen-related protein-1

mfrep-1

Recombinant Fgl1 Proteins

Cat. No. Product Name Accession Purity
HY-P75188 FGL1 Protein, Mouse (sf9, His) Q71KU9 (L23-I314) ≥95%
HY-P75189 FGL1 Protein, Mouse (HEK293, hFc) NP_663569.2 (L23-I314) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99156 Relatlimab 97.56% Phase 3
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04927 FGL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-164308 SA-15-P Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgl1 NCBI NCBI:2267
Macaca fascicularis Fgl1 NCBI NCBI:102118020
Rattus norvegicus Fgl1 NCBI NCBI:246186