TSPAN15 - tetraspanin 15 Gene

Homo sapiens

Also known as NET7; NET-7; TM4SF15; 2700063A19Rik

Gene ID: 23555 | Gene type: protein coding

About TSPAN15

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:69,451,465-69,549,508 (from NCBI)

This gene has 8 transcripts (splice variants), 204 orthologues and 32 paralogues. Broad expression in fat (RPKM 7.7), stomach (RPKM 7.1) and 21 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

TSPAN15 Products(2)

mRNA	Protein	Name
NM_001351263.2	NP_001338192.1	tetraspanin-15 isoform 2
NM_012339.5	NP_036471.1	tetraspanin-15 isoform 1

TSPAN15 Protein Structure

Tetraspannin

0
100
200
294 a.a.

Protein Preferred Names

Protein Names

tetraspanin-15

tetraspan NET-7

TSPAN15 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TSPAN15	O95858	STRIT1	Homo sapiens	P0DN84	Validated Y2H	32296183
Intra	TSPAN15	O95858	ADAM10	Homo sapiens	O14672	Anti Bait CoIP	26686862
Intra	TSPAN15	O95858	ADAM10	Homo sapiens	O14672	Anti Tag CoIP	26686862
Intra	TSPAN15	O95858	ADAM10	Homo sapiens	O14672	Anti Tag CoIP	33961781
Intra	TSPAN15	O95858	GYPC	Homo sapiens	P04921	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Femoral Vein Thrombophlebitis

Phlebitis And Thrombophlebitis Of Femoral Vein	Thrombophlebitis Of The Femoral Vein
Thrombophlebitis Of Deep Femoral Vein

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15163	TSPAN15 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TSPAN15	VGNC	VGNC:36430
Felis catus	TSPAN15	VGNC	VGNC:66627
Rattus norvegicus	TSPAN15	RGD	RGD:1588304
Canis familiaris	TSPAN15	VGNC	VGNC:47915
Mus musculus	TSPAN15	MGD	MGI:1917673
Macaca mulatta	TSPAN15	VGNC	VGNC:79385

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