2. Gene
  3. Lrrc4c - leucine rich repeat containing 4C Gene

Lrrc4c - leucine rich repeat containing 4C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NGL-1; 6430556C10Rik

Gene ID: 241568 | Gene type: protein coding

About Lrrc4c

Summary

Predicted to enable cell-cell adhesion mediator activity. Involved in modulation of chemical synaptic transmission and synaptic membrane adhesion. Located in Schaffer collateral - CA1 synapse. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Is expressed in central nervous system and eye. Orthologous to human LRRC4C (leucine rich repeat containing 4C). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc4c Products(7)

mRNA Protein Name
NM_001289742.1 NP_001276671.1 leucine-rich repeat-containing protein 4C precursor
NM_001289743.1 NP_001276672.1 leucine-rich repeat-containing protein 4C precursor
NM_001289744.1 NP_001276673.1 leucine-rich repeat-containing protein 4C precursor
NM_001363047.1 NP_001349976.1 leucine-rich repeat-containing protein 4C precursor
NM_001363048.1 NP_001349977.1 leucine-rich repeat-containing protein 4C precursor
NM_001363049.1 NP_001349978.1 leucine-rich repeat-containing protein 4C precursor
NM_178725.6 NP_848840.3 leucine-rich repeat-containing protein 4C precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15590698 MGI
Biological Process GO Annotation Evidence Reference Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
25411505 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
25411505 MGI
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
25411505 MGI
involved in synaptic membrane adhesion IEP
IEP: Inferred from expression pattern
25411505 MGI
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
25411505 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
25411505 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25411505 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
25411505 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25411505 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
25411505 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 4C

netrin-G1 ligand

Lrrc4c Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Lrrc4c Q8C031 Whrn Mus musculus Q80VW5
Pull Down
15590698
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Lrrc4c Proteins

Cat. No. Product Name Accession Purity
HY-P77103 NGL-1/LRRC4C Protein, Mouse (HEK293, His) Q8C031/BAC27884.1 (Q45-K527) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07822 LRRC4C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrc4c NCBI NCBI:57689