2. Gene
  3. Acr - acrosin Gene

Acr - acrosin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Acro

Gene ID: 24163 | Gene type: protein coding

About Acr

Summary

Predicted to enable amidase activity; monosaccharide binding activity; and serine-type endopeptidase activity. Involved in acrosome matrix dispersal; penetration of zona pellucida; and response to steroid hormone. Located in Golgi-associated vesicle and acrosomal vesicle. Orthologous to human ACR (acrosin). [provided by Alliance of Genome Resources, Apr 2022]

Acr Products(1)

mRNA Protein Name
NM_012490.2 NP_036622.2 acrosin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in acrosome matrix dispersal IMP
IMP: Inferred from mutant phenotype
28859281 RGD
involved in penetration of zona pellucida IMP
IMP: Inferred from mutant phenotype
28859281 RGD
involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
28859281 RGD
involved in response to steroid hormone IDA
IDA: Inferred from direct assay
9838878 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Golgi-associated vesicle IDA
IDA: Inferred from direct assay
8601690 RGD
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
8601690 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acrosin

acrosin prepropeptide

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-10684 Pridopidine Antagonist 99.85% Phase 3
HY-19845 Ordopidine Antagonist / Phase 1
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-129126 NC9 Inhibitor / Unkown
HY-RS00193 ACR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-111210 Pridopidine hydrochloride Antagonist / Unkown
HY-19845A Ordopidine hydrochloride Modulator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acr NCBI NCBI:49
Canis familiaris Acr NCBI NCBI:606765
Macaca fascicularis Acr NCBI NCBI:102115325
Mus musculus Acr NCBI NCBI:11434
Macaca mulatta Acr NCBI NCBI:716579