Alb - albumin Gene

Rattus norvegicus

Also known as Alb1; Albza

Gene ID: 24186 | Gene type: protein coding

About Alb

Summary

Enables several functions, including fatty acid binding activity; modified amino acid binding activity; and zinc ion binding activity. Involved in several processes, including positive regulation of circadian sleep/wake cycle, non-REM sleep; response to mercury ion; and response to platinum ion. Located in basement membrane and extracellular space. Used to study familial hyperlipidemia. Biomarker of Reye syndrome; obstructive jaundice; and protein-energy malnutrition. Human ortholog(s) of this gene implicated in several diseases, including biliary tract benign neoplasm; hepatobiliary system Cancer (multiple); hyperthyroxinemia; middle cerebral artery infarction; and psoriasis. Orthologous to human ALB (albumin). [provided by Alliance of Genome Resources, Apr 2022]

Alb Products(1)

mRNA	Protein	Name
NM_134326.2	NP_599153.2	albumin precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	10350214	RGD
enables fatty acid binding	IDA IDA: Inferred from direct assay	16753933	RGD
enables modified amino acid binding	IPI IPI: Inferred from physical interaction	12458670	RGD
enables zinc ion binding	IDA IDA: Inferred from direct assay	540055	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of circadian sleep/wake cycle, non-REM sleep	IDA IDA: Inferred from direct assay	9748091	RGD
involved in response to biphenyl	IEP IEP: Inferred from expression pattern	12051991	RGD
involved in response to mercury ion	IEP IEP: Inferred from expression pattern	17184894	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	20227002	RGD
involved in response to platinum ion	IEP IEP: Inferred from expression pattern	19425235	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in basement membrane	IDA IDA: Inferred from direct assay	1723977	RGD
located in extracellular space	IDA IDA: Inferred from direct assay	17010194	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

albumin

serum albumin

Related Agents

Clinical Phase

Inhibitory Antibodies (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99845	Dazodalibep		99.90%	Phase 3
HY-P990748	Lunsekimig		98.00%	Phase 2
HY-P99385	Vobarilizumab	Inhibitor	97.36%	Phase 2
HY-P990735	Donzakimig		/	Phase 1

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-141536	PSMA-ALB-56		98.92%	Unkown
HY-111398	ALB-127158(a)	Antagonist	99.52%	Unkown
HY-P3112	ICI 216140	Antagonist	99.78%	Unkown
HY-133214	Cyclazosin hydrochloride	Antagonist	/	Unkown
HY-151437	Antifungal agent 40	Inhibitor	/	Unkown
HY-151440	Antifungal agent 42	Inhibitor	/	Unkown
HY-16036A	ALB-109564 hydrochloride	Inhibitor	/	Unkown
HY-RS00556	ALB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990907	Brivekimig	Inhibitor	98%	Unkown
HY-P990920	Gocatamig	Inhibitor	/	Unkown
HY-P990741	Galvokimig		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Alb	NCBI	NCBI:213
Macaca fascicularis	Alb	NCBI	NCBI:102130757
Mus musculus	Alb	NCBI	NCBI:11657
Leporidae	Alb	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.