2. Gene
  3. Klkb1 - kallikrein B1 Gene

Klkb1 - kallikrein B1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PK; Klk3; Kalp1; KALP15

Gene ID: 25048 | Gene type: protein coding

About Klkb1

Summary

Predicted to enable serine-type endopeptidase activity. Involved in liver regeneration. Located in extracellular space. Used to study inflammatory bowel disease. Biomarker of liver cirrhosis. Human ortholog(s) of this gene implicated in lupus nephritis and systemic lupus erythematosus. Orthologous to human KLKB1 (Kallikrein B1). [provided by Alliance of Genome Resources, Apr 2022]

Klkb1 Products(1)

mRNA Protein Name
NM_012725.2 NP_036857.2 plasma kallikrein precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in liver regeneration IEP
IEP: Inferred from expression pattern
9869390 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
9783057 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plasma kallikrein

fletcher factor

kallikrein B, plasma 1

kininogenin

plasma prekallikrein

Recombinant Klkb1 Proteins

Cat. No. Product Name Accession Purity
HY-P71748 Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His) P14272 (391I-638A) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148949A Kallikrein 5-IN-2 TFA Inhibitor 99.53% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klkb1 NCBI NCBI:3818
Macaca fascicularis Klkb1 NCBI NCBI:102142369
Mus musculus Klkb1 NCBI NCBI:16621