2. Gene
  3. Efnb1 - ephrin B1 Gene

Efnb1 - ephrin B1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as EFL-3; LERK2

Gene ID: 25186 | Gene type: protein coding

About Efnb1

Summary

Predicted to enable Ephrin Receptor binding activity. Involved in presynapse assembly. Located in synapse. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome and dysostosis. Orthologous to human EFNB1 (ephrin B1). [provided by Alliance of Genome Resources, Apr 2022]

Efnb1 Products(1)

mRNA Protein Name
NM_017089.3 NP_058785.2 ephrin-B1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9883737 RGD
Biological Process GO Annotation Evidence Reference Source
involved in nervous system development IMP
IMP: Inferred from mutant phenotype
12139920 RGD
involved in presynapse assembly IDA
IDA: Inferred from direct assay
19915143 RGD
involved in presynapse assembly IMP
IMP: Inferred from mutant phenotype
19915143 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19915143 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
19915143 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
19915143 RGD
located in synapse IDA
IDA: Inferred from direct assay
9883737 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin-B1

ELK ligand

ELK-L

EPH-related receptor tyrosine kinase ligand 2

LERK-2

Recombinant Efnb1 Proteins

Cat. No. Product Name Accession Purity
HY-P73029 Ephrin-B1/EFNB1 Protein, Rat (HEK293, Fc) P52796 (A25-T229) ≥95%
HY-P73030 Ephrin-B1/EFNB1 Protein, Rat (HEK293, His) P52796 (A25-T229) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04197 EFNB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efnb1 NCBI NCBI:1947
Mus musculus Efnb1 NCBI NCBI:13641