2. Gene
  3. Pdgfa - platelet derived growth factor subunit A Gene

Pdgfa - platelet derived growth factor subunit A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PDGFACP

Gene ID: 25266 | Gene type: protein coding

About Pdgfa

Summary

Predicted to enable several functions, including platelet-derived growth factor binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in several processes, including male gonad development; response to estradiol; and response to retinoic acid. Predicted to be located in cell surface and microvillus. Predicted to be active in extracellular space. Biomarker of chronic ulcer of skin; oligohydramnios; pancreatitis; pulmonary hypertension; and renovascular hypertension. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfa Products(1)

mRNA Protein Name
NM_012801.2 NP_036933.2 platelet-derived growth factor subunit A precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: Inferred from expression pattern
16039137 RGD
involved in inner ear development IEP
IEP: Inferred from expression pattern
15267171 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
11870082 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15267171 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
14724432 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
8447423 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
15315332 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16414398 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-derived growth factor subunit A

PDGF subunit A

PDGF-1

Platelet-derived growth factor A chain

platelet derived growth factor, alpha

platelet-derived growth factor alpha polypeptide

Recombinant Pdgfa Proteins

Cat. No. Product Name Accession Purity
HY-P73720 PDGF-AA Protein, Rat (P.pastoris, His) P28576-2/NP_036933.2 (S87-R196) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10250 PDGFA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdgfa NCBI NCBI:5154
Canis familiaris Pdgfa NCBI NCBI:491597
Mus musculus Pdgfa NCBI NCBI:18590