2. Gene
  3. CD80 - Cd80 Cd80 molecule Gene

CD80 - Cd80 Cd80 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as B7-1

Gene ID: 25408 | Gene type: protein coding

About CD80

Summary

Predicted to enable coreceptor activity. Involved in positive regulation of T cell proliferation. Located in cell surface. Used to study adult T-cell leukemia; anti-basement membrane glomerulonephritis; high grade glioma; and periodontal disease. Biomarker of kidney failure. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CD80 (CD80 molecule). [provided by Alliance of Genome Resources, Apr 2022]

CD80 Products(1)

mRNA Protein Name
NM_012926.2 NP_037058.2 T-lymphocyte activation antigen CD80
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of T cell proliferation IMP
IMP: Inferred from mutant phenotype
9237108 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
15474526 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-lymphocyte activation antigen CD80

CD80 antigen

CD80-like

Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1)

Recombinant CD80 Proteins

Cat. No. Product Name Accession Purity
HY-P7634 B7-1/CD80 Protein, Rat (HEK293, His) O35187 (V30-Q248) ≥95%
HY-P74398 B7-1/CD80 Protein, Rat (HEK293, Fc) AAB60503 (M1-Q248) ≥95%

CD80 Antibodies

Cat. No. Product Name Application Reactivity
HY-P81184 CD80 Antibody (YA3386) WB, IHC-P, FC, ICC/IF Human, Mouse

Related Agents

Approval
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9919 Durvalumab Inhibitor 99.60% Unkown
Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99293 Galiximab Inhibitor 99.23% Phase 3
HY-P99844 Davoceticept / Phase 1
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103048A PD-1/PD-L1-IN 3 TFA Inhibitor 99.34% Unkown
HY-150749A ODN D-SL03 sodium 99.82% Unkown
HY-150749 ODN D-SL03 Inducer 99.82% Unkown
HY-100891 CD80-IN-3 98.08% Unkown
HY-103048 PD-1/PD-L1-IN 3 Inhibitor / Unkown
HY-160227 ORN 06 Activator / Unkown
HY-161833 HSP90-IN-31 Inhibitor / Unkown
HY-RS02269 CD80 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-168384 M04 / Unkown
HY-169819 Calcium influx inducer compound 634 / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9919A Durvalumab (anti-PD-L1) Inhibitor 99.90% Unkown
HY-P990127 Anti-Mouse CD80/B7-1 Antibody (RM80) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CD80 NCBI NCBI:941
Macaca fascicularis CD80 NCBI NCBI:102140078
Mus musculus CD80 NCBI NCBI:12519
Leporidae CD80 NCBI
Macaca mulatta CD80 NCBI NCBI:732518