2. Gene
  3. TCP11L2 - t-complex 11 like 2 Gene

TCP11L2 - t-complex 11 like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 255394 | Gene type: protein coding

About TCP11L2

Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:106,297,935-106,347,003 (from NCBI)

This gene has 10 transcripts (splice variants), 208 orthologues and 4 paralogues. Ubiquitous expression in esophagus (RPKM 5.7), lung (RPKM 5.0) and 25 other tissues.

Summary

Predicted to be involved in signal transduction. [provided by Alliance of Genome Resources, Apr 2022]

TCP11L2 Products(2)

mRNA Protein Name
NM_001286262.2 NP_001273191.1 T-complex protein 11-like protein 2 isoform 2
NM_152772.3 NP_689985.1 T-complex protein 11-like protein 2 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TCP11L2 Protein Structure

Tcp11

Tcp11: T-complex protein 11 (77 - 501)

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  • 519 a.a.
Protein Preferred Names Protein Names

T-complex protein 11-like protein 2

t-complex 11, testis-specific-like 2

TCP11L2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TCP11L2 Q8N4U5 CXXC1 Homo sapiens Q9P0U4-2
Validated Y2H
32296183
Intra
TCP11L2 Q8N4U5 TUBA4A Homo sapiens P68366
Y2H Prey Pooling
32296183
Intra
TCP11L2 Q8N4U5 TUBA4A Homo sapiens P68366
Y2H Array
32296183
Intra
TCP11L2 Q8N4U5 TUBA8 Homo sapiens Q9NY65
Y2H Prey Pooling
32296183
Intra
TCP11L2 Q8N4U5 TUBA8 Homo sapiens Q9NY65
Y2H Array
32296183
Intra
TCP11L2 Q8N4U5 TUBA8 Homo sapiens Q9NY65
Validated Y2H
32296183
Intra
TCP11L2 Q8N4U5 ACTA2 Homo sapiens P62736
Anti Tag CoIP
33961781
Intra
TCP11L2 Q8N4U5 ACTA2 Homo sapiens P62736
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14324 TCP11L2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TCP11L2 VGNC VGNC:47210
Macaca mulatta TCP11L2 VGNC VGNC:79729
Felis catus TCP11L2 VGNC VGNC:66037
Rattus norvegicus TCP11L2 RGD RGD:1307494
Mus musculus TCP11L2 MGD MGI:2444679
Bos taurus TCP11L2 VGNC VGNC:35704