STEAP1B - STEAP family member 1B Gene

Homo sapiens

Gene ID: 256227 | Gene type: protein coding

About STEAP1B

This gene has 10 transcripts (splice variants), 143 orthologues and 4 paralogues. Broad expression in prostate (RPKM 3.5), appendix (RPKM 1.8) and 15 other tissues.

Summary

Predicted to be integral component of membrane. Predicted to be active in endosome and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

STEAP1B Products(3)

mRNA	Protein	Name
NM_001164460.2	NP_001157932.1	STEAP family member 1B isoform 1
NM_001382447.1	NP_001369376.1	STEAP family member 1B isoform 3
NM_207342.3	NP_997225.1	STEAP family member 1B isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STEAP1B Protein Structure

Ferric_reduct

0
100
200
245 a.a.

Protein Preferred Names

Protein Names

STEAP family member 1B

STEAP family protein MGC87042

STEAP1B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	STEAP1B	Q6NZ63	STEAP1	Homo sapiens	Q9UHE8	Anti Tag CoIP	33961781
Intra	STEAP1B	Q6NZ63	STEAP1	Homo sapiens	Q9UHE8	Anti Tag CoIP	28514442
Intra	STEAP1B	Q6NZ63	FOXD4L6	Homo sapiens	Q3SYB3	Validated Y2H	32814053
Intra	STEAP1B	Q6NZ63	FOXD4L6	Homo sapiens	Q3SYB3	Y2H Pooling	32814053
Intra	STEAP1B	Q6NZ63	FOXD4L6	Homo sapiens	Q3SYB3	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Ewing Sarcoma Of Bone

Ewing'S Sarcoma Of Bone	Bone Ewing Sarcoma
Bone Ewing'S Sarcoma	Bone Localized Ewing Sarcoma
Bone Localized Ewing'S Sarcoma	Ewing'S Sarcoma/Bone Peripheral Primitive Neuroectodermal Tumor
Localized Skeletal Ewing'S Sarcoma	Localized Bone Ewing Sarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13906	STEAP1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	STEAP1B	MGD	MGI:1917608

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