2. Gene
  3. ARHGAP30 - Rho GTPase activating protein 30 Gene

ARHGAP30 - Rho GTPase activating protein 30 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 257106 | Gene type: protein coding

About ARHGAP30

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,046,946-161,069,891 (from NCBI)

This gene has 7 transcripts (splice variants), 126 orthologues and 3 paralogues. Broad expression in lymph node (RPKM 43.4), spleen (RPKM 39.2) and 17 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase mediated signal transduction. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

ARHGAP30 Products(4)

mRNA Protein Name
NM_001025598.2 NP_001020769.1 rho GTPase-activating protein 30 isoform 1
NM_001287600.2 NP_001274529.1 rho GTPase-activating protein 30 isoform 3
NM_001287602.2 NP_001274531.1 rho GTPase-activating protein 30 isoform 4
NM_181720.3 NP_859071.2 rho GTPase-activating protein 30 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21565175 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARHGAP30 Protein Structure

RhoGAP

RhoGAP: RhoGAP domain (34 - 182)

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  • 1101 a.a.
Protein Preferred Names Protein Names

rho GTPase-activating protein 30

rho-type GTPase-activating protein 30

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00929 ARHGAP30 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ARHGAP30 RGD RGD:1561419
Bos taurus ARHGAP30 VGNC VGNC:26088
Canis familiaris ARHGAP30 VGNC VGNC:38057
Felis catus ARHGAP30 VGNC VGNC:59887
Macaca mulatta ARHGAP30 VGNC VGNC:99847
Mus musculus ARHGAP30 MGD MGI:2684948