RSL1D1 - ribosomal L1 domain containing 1 Gene

Homo sapiens

Also known as L12; CSIG; PBK1; UTP30

Gene ID: 26156 | Gene type: protein coding

About RSL1D1

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,833,850-11,851,542 (from NCBI)

This gene has 12 transcripts (splice variants), 210 orthologues and 3 paralogues. Ubiquitous expression in ovary (RPKM 45.7), lymph node (RPKM 20.2) and 25 other tissues.

Summary

Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Involved in regulation of apoptotic process and regulation of cellular senescence. Acts upstream of or within regulation of protein localization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

RSL1D1 Products(1)

mRNA	Protein	Name
NM_015659.3	NP_056474.2	ribosomal L1 domain-containing protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	16213212	GOA
enables mRNA 5'-UTR binding	IDA IDA: Inferred from direct assay	16213212	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	30021884	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of apoptotic process	IDA IDA: Inferred from direct assay	18678645	GOA
involved in regulation of cellular senescence	IDA IDA: Inferred from direct assay	18678645	GOA
acts upstream of or within regulation of protein localization	IMP IMP: Inferred from mutant phenotype	17158916	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleolus	IDA IDA: Inferred from direct assay	18678645	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RSL1D1 Protein Structure

Ribosomal_L1

0
100
200
300
400
490 a.a.

Protein Preferred Names

Protein Names

ribosomal L1 domain-containing protein 1

CATX-11

RSL1D1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	RSL1D1	O76021	RPL7A	Homo sapiens	P62424	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Bowen-Conradi Syndrome

BWCNS	Bowen Hutterite Syndrome
Bowen-Conradi Hutterite Syndrome	Bowen Syndrome, Hutterite Type
Bowen Hutterite Syndrome, Formerly	Hutterite Syndrome
Bowen Syndrome Hutterite Type	Fetal Growth Retardation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12300	RSL1D1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RSL1D1	VGNC	VGNC:34180
Mus musculus	RSL1D1	MGD	MGI:1913659
Rattus norvegicus	RSL1D1	RGD	RGD:1359295
Canis familiaris	RSL1D1	VGNC	VGNC:45775
Macaca mulatta	RSL1D1	VGNC	VGNC:77096
Felis catus	RSL1D1	VGNC	VGNC:64789

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