2. Gene
  3. PPP1R14B - protein phosphatase 1 regulatory inhibitor subunit 14B Gene

PPP1R14B - protein phosphatase 1 regulatory inhibitor subunit 14B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PNG; PHI-1; PLCB3N; SOM172

Gene ID: 26472 | Gene type: protein coding

About PPP1R14B

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,244,479-64,246,943 (from NCBI)

This gene has 3 transcripts (splice variants), 226 orthologues and 3 paralogues. Ubiquitous expression in skin (RPKM 28.9), appendix (RPKM 28.1) and 25 other tissues.

Summary

Predicted to enable protein serine/threonine Phosphatase Inhibitor activity. Predicted to be involved in innate immune response. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PPP1R14B Products(1)

mRNA Protein Name
NM_138689.3 NP_619634.1 protein phosphatase 1 regulatory subunit 14B
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32707033 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPP1R14B Protein Structure

PP1_inhibitor

PP1_inhibitor: PKC-activated protein phosphatase-1 inhibitor (49 - 145)

  • 0
  • 100
  • 147 a.a.
Protein Preferred Names Protein Names

protein phosphatase 1 regulatory subunit 14B

phospholipase C beta-3 neighboring gene protein

PPP1R14B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra PPP1R14B Q96C90 LIMK2 Homo sapiens P53671
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10984 PPP1R14B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PPP1R14B RGD RGD:628702
Felis catus PPP1R14B VGNC VGNC:81956
Mus musculus PPP1R14B MGD MGI:107682
Canis familiaris PPP1R14B VGNC VGNC:56092