RANBP6 - RAN binding protein 6 Gene

Homo sapiens

Gene ID: 26953 | Gene type: protein coding

About RANBP6

This gene has 3 transcripts (splice variants), 59 orthologues and 5 paralogues. Ubiquitous expression in bone marrow (RPKM 13.1), brain (RPKM 11.6) and 25 other tissues.

Summary

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RANBP6 Products(3)

mRNA	Protein	Name
NM_001243202.2	NP_001230131.1	ran-binding protein 6 isoform 2
NM_001243203.2	NP_001230132.1	ran-binding protein 6 isoform 3
NM_012416.4	NP_036548.1	ran-binding protein 6 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22190034	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RANBP6 Protein Structure

HEAT_2

HEAT

0
200
400
600
800
1000
1105 a.a.

Protein Preferred Names

Protein Names

ran-binding protein 6

Ran-GTP binding protein

RANBP6 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	RANBP6	O60518	q76353_9hiv1	Human immunodeficiency virus	Q76353	Pull Down	22190034

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Primary Mediastinal B-Cell Lymphoma

Large Cell Lymphoma Of The Mediastinum	Mediastinal Diffuse Large-Cell Lymphoma With Sclerosis
Primary Mediastinal Clear Cell Lymphoma Of B-Cell Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11648	RANBP6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RANBP6	VGNC	VGNC:50254
Rattus norvegicus	RANBP6	RGD	RGD:1305165
Mus musculus	RANBP6	MGD	MGI:2683212

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