2. Gene
  3. FETUB - fetuin B Gene

FETUB - fetuin B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 16G2; Gugu; IRL685

Gene ID: 26998 | Gene type: protein coding

About FETUB

Cytogenetic location: 3q27.3 Genomic coordinates (GRCh38): 3:186,635,969-186,653,141 (from NCBI)

This gene has 8 transcripts (splice variants), 268 orthologues and 3 paralogues. Restricted expression toward liver (RPKM 42.7).

Summary

The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine Protease Inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the Insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008]

FETUB Products(9)

mRNA Protein Name
NM_001308077.4 NP_001295006.1 fetuin-B isoform 2 precursor
NM_001308079.4 NP_001295008.1 fetuin-B isoform 3 precursor
NM_001375587.2 NP_001362516.1 fetuin-B isoform 1 precursor
NM_001375588.2 NP_001362517.1 fetuin-B isoform 5
NM_001375589.2 NP_001362518.1 fetuin-B isoform 6
NM_001375590.2 NP_001362519.1 fetuin-B isoform 6
NM_001375591.2 NP_001362520.1 fetuin-B isoform 6
NM_001375592.2 NP_001362521.1 fetuin-B isoform 6
NM_014375.3 NP_055190.2 fetuin-B isoform 1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FETUB Protein Structure

Cystatin

Cystatin: Cystatin domain (37 - 120)

Cystatin

Cystatin: Cystatin domain (158 - 246)

  • 0
  • 100
  • 200
  • 300
  • 382 a.a.
Protein Preferred Names Protein Names

fetuin-B

fetuin-like protein IRL685

Recombinant FETUB Proteins

Cat. No. Product Name Accession Purity
HY-P70930 Fetuin B Protein, Human (HEK293, His) Q9UGM5-1 (C16-P382) ≥95%

Related Diseases

Diseases Alias
Encephalitozoonosis

Infection By Encephalitozoon
Caffey Disease

Infantile Cortical Hyperostosis

CAFYD

Cortical Congenital Hyperostosis

Caffey-Silverman Syndrome

De Toni-Caffey Disease

Hyperostosis Cortical Infantile

Hyperostosis, Cortical, Congenital
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04868 FETUB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FETUB VGNC VGNC:40826
Rattus norvegicus FETUB RGD RGD:69293
Felis catus FETUB VGNC VGNC:62233
Mus musculus FETUB MGD MGI:1890221
Bos taurus FETUB VGNC VGNC:28955
Macaca mulatta FETUB VGNC VGNC:72638
Others FETUB NCBI