GPR162 - G protein-coupled receptor 162 Gene

Homo sapiens

Also known as A-2; GRCA

Gene ID: 27239 | Gene type: protein coding

About GPR162

This gene has 7 transcripts (splice variants), 117 orthologues and 1 paralogue. Biased expression in brain (RPKM 25.8), lung (RPKM 3.5) and 6 other tissues.

Summary

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GPR162 Products(2)

mRNA	Protein	Name
NM_014449.2	NP_055264.1	probable G-protein coupled receptor 162 isoform 1
NM_019858.2	NP_062832.1	probable G-protein coupled receptor 162 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR162 Protein Structure

7tm_1

0
100
200
300
400
500
588 a.a.

Protein Preferred Names

Protein Names

probable G-protein coupled receptor 162

gene rich cluster, A

GPR162 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GPR162	Q16538	UBQLN1	Homo sapiens	Q9UMX0	Y2H Prey Pooling	32296183
Intra	GPR162	Q16538	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32296183
Intra	GPR162	Q16538	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32296183
Intra	GPR162	Q16538	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	GPR162	Q16538	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	GPR162	Q16538	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Fanconi Anemia, Complementation Group C

Fanconi Anemia Complementation Group C	FANCC
Facc	Fac
Fa3	Fanconi Pancytopenia Type 3
Fanconi Pancytopenia, Type 3	Faces Syndrome
Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies	Friedman-Goodman Syndrome
Abnormality Of The Face

Vitreous Detachment

Posterior Vitreous Detachment

Vitreous Syneresis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05678	GPR162 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GPR162	VGNC	VGNC:99934
Canis familiaris	GPR162	VGNC	VGNC:41413
Mus musculus	GPR162	MGD	MGI:1315214
Rattus norvegicus	GPR162	RGD	RGD:1307437
Bos taurus	GPR162	VGNC	VGNC:29567
Felis catus	GPR162	VGNC	VGNC:62685

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