2. Gene
  3. RRP7A - ribosomal RNA processing 7 homolog A Gene

RRP7A - ribosomal RNA processing 7 homolog A Gene

  • Gene
  • Protein
Homo sapiens (human)

Also known as Rrp7; CGI-96; MCPH28; BK126B4.3

Gene ID: 27341 | Gene type: protein coding

About RRP7A

Summary

Enables RNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to act upstream of or within blastocyst formation. Predicted to be located in nucleoplasm. Predicted to be part of CURI complex and UTP-C complex. Implicated in primary autosomal recessive microcephaly. [provided by Alliance of Genome Resources, Apr 2022]

RRP7A Products(1)

mRNA Protein Name
NM_015703.5 NP_056518.2 ribosomal RNA-processing protein 7 homolog A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cilium disassembly IMP
IMP: Inferred from mutant phenotype
33199730 GOA
involved in protein localization to nucleolus IMP
IMP: Inferred from mutant phenotype
33199730 GOA
involved in rRNA processing IMP
IMP: Inferred from mutant phenotype
33199730 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
involved in ribosome biogenesis IMP
IMP: Inferred from mutant phenotype
33199730 GOA
Cellular Component GO Annotation Evidence Reference Source
located in centrosome IDA
IDA: Inferred from direct assay
33199730 GOA
located in cilium IDA
IDA: Inferred from direct assay
33199730 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
33199730 GOA
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribosomal RNA-processing protein 7 homolog A

CTA-126B4.5

gastric cancer antigen Zg14

RRP7A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
RRP7A Q9Y3A4 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
RRP7A Q9Y3A4 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
RRP7A Q9Y3A4 CDCA7L Homo sapiens Q96GN5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction