MAJIN - membrane anchored junction protein Gene

Homo sapiens

Also known as C11orf85

Gene ID: 283129 | Gene type: protein coding

About MAJIN

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,938,230-64,972,108 (from NCBI)

This gene has 6 transcripts (splice variants) and 113 orthologues. Restricted expression toward testis (RPKM 5.4).

Summary

Predicted to enable DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Predicted to be located in chromosome, telomeric region. Predicted to be integral component of nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

MAJIN Products(3)

mRNA	Protein	Name
NM_001037225.3	NP_001032302.1	membrane-anchored junction protein isoform 1
NM_001300803.2	NP_001287732.1	membrane-anchored junction protein isoform 2
NM_001318808.2	NP_001305737.1	membrane-anchored junction protein isoform 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAJIN Protein Structure

MAJIN

0
100
200
216 a.a.

Protein Preferred Names

Protein Names

membrane-anchored junction protein

MAJIN Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MAJIN	Q3KP22	CRYBB3	Homo sapiens	P26998	Anti Tag CoIP	33961781
Intra	MAJIN	Q3KP22	CRYBB3	Homo sapiens	P26998	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07988	MAJIN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MAJIN	MGD	MGI:1923913
Rattus norvegicus	MAJIN	RGD	RGD:1563886
Macaca mulatta	MAJIN	VGNC	VGNC:74375
Bos taurus	MAJIN	VGNC	VGNC:31151
Felis catus	MAJIN	VGNC	VGNC:63368

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