GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

Homo sapiens

Also known as GluD1; GluD1-b

Gene ID: 2894 | Gene type: protein coding

About GRID1

Cytogenetic location: 10q23.1-q23.2 Genomic coordinates (GRCh38): 10:85,599,552-86,366,795 (from NCBI)

This gene has 3 transcripts (splice variants), 329 orthologues and 17 paralogues. Biased expression in brain (RPKM 6.7), thyroid (RPKM 3.7) and 12 other tissues.

Summary

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]

GRID1 Products(1)

mRNA	Protein	Name
NM_017551.3	NP_060021.1	glutamate receptor ionotropic, delta-1 precursor

GRID1 Protein Structure

ANF_receptor

SBP_bac_3

Lig_chan

0
200
400
600
800
1009 a.a.

Protein Preferred Names

Protein Names

glutamate receptor ionotropic, delta-1

gluR delta-1 subunit

GRID1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GRID1	Q9ULK0	HBB	Homo sapiens	P68871	Anti Tag CoIP	28514442
Intra	GRID1	Q9ULK0	HBB	Homo sapiens	P68871	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Chromosome 17q21.31 Duplication Syndrome

17q21.31 Microduplication Syndrome	Trisomy 17q21.31
Dup(17)(Q21.31)

Rett Syndrome

Atypical Rett Syndrome	RTT
Rett Disorder	Rts
Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use	Rett Syndrome, Preserved Speech Variant
Rett Syndrome, Atypical	Rett'S Disorder
Rett Syndrome Variant	Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome
Cerebroatrophic Hyperammonemia	Rett Like Syndrome
Rett'S Syndrome	Atypical Rtt
Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use	Rett Syndrome Preserved Speech Variant
Rett Syndrome Zappella Variant	Rett Syndrome, Zappella Variant

Diaphragmatic Eventration

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05795	GRID1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	GRID1	VGNC	VGNC:55986
Rattus norvegicus	GRID1	RGD	RGD:68366
Macaca mulatta	GRID1	VGNC	VGNC:73275
Felis catus	GRID1	VGNC	VGNC:67464
Mus musculus	GRID1	MGD	MGI:95812
Canis familiaris	GRID1	VGNC	VGNC:51898

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