2. Gene
  3. GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GluD1; GluD1-b

Gene ID: 2894 | Gene type: protein coding

About GRID1

Cytogenetic location: 10q23.1-q23.2 Genomic coordinates (GRCh38): 10:85,599,552-86,366,795 (from NCBI)

This gene has 3 transcripts (splice variants), 329 orthologues and 17 paralogues. Biased expression in brain (RPKM 6.7), thyroid (RPKM 3.7) and 12 other tissues.

Summary

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]

GRID1 Products(1)

mRNA Protein Name
NM_017551.3 NP_060021.1 glutamate receptor ionotropic, delta-1 precursor

GRID1 Protein Structure

ANF_receptor

ANF_receptor: Receptor family ligand binding region (40 - 397)

SBP_bac_3

SBP_bac_3: Bacterial extracellular solute-binding proteins, family 3 (446 - 805)

Lig_chan

Lig_chan: Ligand-gated ion channel (564 - 842)

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  • 1009 a.a.
Protein Preferred Names Protein Names

glutamate receptor ionotropic, delta-1

gluR delta-1 subunit

Related Diseases

Diseases Alias
Chromosome 17q21.31 Duplication Syndrome

17q21.31 Microduplication Syndrome

Trisomy 17q21.31

Dup(17)(Q21.31)
Rett Syndrome

Atypical Rett Syndrome

RTT

Rett Disorder

Rts

Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use

Rett Syndrome, Preserved Speech Variant

Rett Syndrome, Atypical

Rett'S Disorder

Rett Syndrome Variant

Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome

Cerebroatrophic Hyperammonemia

Rett Like Syndrome

Rett'S Syndrome

Atypical Rtt

Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use

Rett Syndrome Preserved Speech Variant

Rett Syndrome Zappella Variant

Rett Syndrome, Zappella Variant
Diaphragmatic Eventration
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05795 GRID1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GRID1 VGNC VGNC:55986
Rattus norvegicus GRID1 RGD RGD:68366
Macaca mulatta GRID1 VGNC VGNC:73275
Felis catus GRID1 VGNC VGNC:67464
Mus musculus GRID1 MGD MGI:95812
Canis familiaris GRID1 VGNC VGNC:51898