2. Gene
  3. Pbk - PDZ binding kinase Gene

Pbk - PDZ binding kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 290326 | Gene type: protein coding

About Pbk

Primary_assembly 15: 40,023,002-40,034,014 forward strand.mRatBN7.2:CM026988.1

This gene has 1 transcript (splice variant), 208 orthologues and is associated with 2 phenotypes. Biased expression in Testes (RPKM 96.), Thymus (RPKM 81.) and 8 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within several processes, including cellular response to UV; negative regulation of cellular protein metabolic process; and negative regulation of stress-activated MAPK cascade. Predicted to be located in nucleus. Orthologous to human PBK (PDZ binding kinase). [provided by Alliance of Genome Resources, Apr 2022]

Pbk Products(1)

mRNA Protein Name
NM_001079937.1 NP_001073406.1 lymphokine-activated killer T-cell-originated protein kinase

Pbk Protein Structure

PKc_TOPK

PKc_TOPK: cd14001 (31 - 318)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
Protein Preferred Names Protein Names

lymphokine-activated killer T-cell-originated protein kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120346 PBK-IN-9 Inhibitor / Unkown
HY-RS10101 PBK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10102 Pbk Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10103 Pbk Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pbk NCBI NCBI:55872