2. Gene
  3. F11 - coagulation factor XI Gene

F11 - coagulation factor XI Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as LRRGT00086

Gene ID: 290757 | Gene type: protein coding

About F11

Summary

Enables serine-type Aminopeptidase activity. Involved in blood coagulation. Located in extracellular space. Human ortholog(s) of this gene implicated in factor XI deficiency and thrombosis. Orthologous to human F11 (coagulation factor XI). [provided by Alliance of Genome Resources, Apr 2022]

F11 Products(1)

mRNA Protein Name
NM_001411666.1 NP_001398595.1 coagulation factor XI precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables serine-type aminopeptidase activity IDA
IDA: Inferred from direct assay
10899350 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
10899350 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor XI

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-162065 N6F11 Inducer 98.37% Unkown
HY-N0541 Pseudoginsenoside F11 99.87% Unkown
HY-N6650 Isotanshinone IIA ≥98.0% Unkown
HY-19606 Cytogenin Inhibitor / Unkown
HY-RS03478 CYP4F11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04625 F11 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04626 F11R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W472509 11-HETE Activator / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991124 Cenvacibart Ligand / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F11 NCBI NCBI:2160
Canis familiaris F11 NCBI NCBI:475623
Macaca fascicularis F11 NCBI NCBI:102143421
Mus musculus F11 NCBI NCBI:109821
Leporidae F11 NCBI
Macaca mulatta F11 NCBI NCBI:702117