2. Gene
  3. N6AMT1 - N-6 adenine-specific DNA methyltransferase 1 Gene

N6AMT1 - N-6 adenine-specific DNA methyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as KMT9; MTQ2; PrmC; HEMK2; N6AMT; PRED28; C21orf127; m.HsaHemK2P

Gene ID: 29104 | Gene type: protein coding

About N6AMT1

Cytogenetic location: 21q21.3 Genomic coordinates (GRCh38): 21:28,575,598-28,885,367 (from NCBI)

This gene has 3 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in prostate (RPKM 1.2), ovary (RPKM 1.0) and 25 other tissues.

Summary

This gene encodes an N(6)-adenine-specific DNA Methyltransferase. The encoded Enzyme may be involved in the methylation of release factor I during translation termination. This Enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]

N6AMT1 Products(2)

mRNA Protein Name
NM_013240.6 NP_037372.4 methyltransferase N6AMT1 isoform 1
NM_182749.5 NP_877426.4 methyltransferase N6AMT1 isoform 2

N6AMT1 Protein Structure

(49 - 173)

  • 0
  • 100
  • 200
  • 214 a.a.
Protein Preferred Names Protein Names

methyltransferase N6AMT1

HemK methyltransferase family member 2

Recombinant N6AMT1 Proteins

Cat. No. Product Name Accession Purity
HY-P77376 HEMK2 Protein, Human (His) Q9Y5N5-2 (M1-S186) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08984 N6AMT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus N6AMT1 VGNC VGNC:63703
Rattus norvegicus N6AMT1 RGD RGD:1311843
Canis familiaris N6AMT1 VGNC VGNC:59066
Mus musculus N6AMT1 MGD MGI:1915018
Bos taurus N6AMT1 VGNC VGNC:49558
Others N6AMT1 NCBI