2. Gene
  3. Erf - Ets2 repressor factor Gene

Erf - Ets2 repressor factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 292721 | Gene type: protein coding

About Erf

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chorio-allantoic fusion; ectodermal cell differentiation; and trophoblast giant cell differentiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in craniosynostosis. Orthologous to human ERF (ETS2 repressor factor). [provided by Alliance of Genome Resources, Apr 2022]

Erf Products(1)

mRNA Protein Name
NM_001170335.1 NP_001163806.1 ETS domain-containing transcription factor ERF
Protein Preferred Names Protein Names

ETS domain-containing transcription factor ERF

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150090 SRI-41315 Activator 99.68% Unkown
HY-120743 Triplin / Unkown
HY-153176 PAT-IN-1 Inhibitor / Unkown
HY-153177 PAT-IN-2 Inhibitor / Unkown
HY-163938 PROTAC erf3a Degrader-1 / Unkown
HY-163938A PROTAC erf3a Degrader-2 / Unkown
HY-163960 NH2-Ph-NH-cyclohexane-NH-Boc / Unkown
HY-163961A Thalidomide-NH-cyclohexane-NH-Ph-NH2 / Unkown
HY-RS04488 ERF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erf NCBI NCBI:2077
Canis familiaris Erf NCBI NCBI:100687937
Macaca fascicularis Erf NCBI NCBI:102115865
Canis lupus familiaris Erf NCBI
Mus musculus Erf NCBI NCBI:13875
Susscrofa domestica Erf NCBI
Leporidae Erf NCBI
Macaca mulatta Erf NCBI NCBI:709170