2. Gene
  3. Cd22 - CD22 molecule Gene

Cd22 - CD22 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 308501 | Gene type: protein coding

About Cd22

Summary

Predicted to enable CD4 receptor binding activity; protein Phosphatase binding activity; and sialic acid binding activity. Predicted to be involved in several processes, including negative regulation of immunoglobulin production; negative regulation of signal transduction; and regulation of B cell proliferation. Predicted to be located in cell surface and neuronal cell body membrane. Predicted to be active in early endosome; external side of plasma membrane; and recycling endosome. Predicted to be integral component of plasma membrane. Orthologous to human CD22 (CD22 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd22 Products(1)

mRNA Protein Name
NM_001107503.1 NP_001100973.1 B-cell receptor CD22 precursor
Protein Preferred Names Protein Names

B-cell receptor CD22

CD22 antigen

Recombinant Cd22 Proteins

Cat. No. Product Name Accession Purity
HY-P75430 Siglec-2/CD22 Protein, Rat (692a.a, HEK293, His) D3ZD88 (M1-R692) ≥95%
HY-P75431 Siglec-2/CD22 Protein, Rat (692a.a, HEK293, Fc) D3ZD88 (M1-R692) ≥95%

Related Agents

Approval
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99255 Moxetumomab pasudotox Inhibitor / Unkown
Clinical Phase
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99264 Inotuzumab Inhibitor ≥95.0% Phase 4
HY-P99289 Epratuzumab ≥95.0% Phase 3
HY-P99034 Moxetumomab Inhibitor 95.00% Phase 3
HY-P99230 Pinatuzumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-146081 CD22 ligand-1 / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990781 Suciraslimab / Unkown
HY-P99464 Bectumomab / Unkown
HY-P990759 Rezetamig / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd22 NCBI NCBI:933
Macaca fascicularis Cd22 NCBI NCBI:102130968
Mus musculus Cd22 NCBI NCBI:12483
Macaca mulatta Cd22 NCBI NCBI:106994739