2. Gene
  3. HSD17B2 - hydroxysteroid 17-beta dehydrogenase 2 Gene

HSD17B2 - hydroxysteroid 17-beta dehydrogenase 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HSD17; SDR9C2; EDH17B2

Gene ID: 3294 | Gene type: protein coding

About HSD17B2

Cytogenetic location: 16q23.3 Genomic coordinates (GRCh38): 16:82,035,253-82,098,534 (from NCBI)

This gene has 6 transcripts (splice variants), 171 orthologues and 25 paralogues. Biased expression in duodenum (RPKM 177.2), placenta (RPKM 169.8) and 6 other tissues.

Summary

Enables estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Involved in response to retinoic acid. Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

HSD17B2 Products(1)

mRNA Protein Name
NM_002153.3 NP_002144.1 17-beta-hydroxysteroid dehydrogenase type 2

HSD17B2 Protein Structure

adh_short

adh_short: short chain dehydrogenase (83 - 250)

  • 0
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  • 300
  • 387 a.a.
Protein Preferred Names Protein Names

17-beta-hydroxysteroid dehydrogenase type 2

17-beta-HSD 2

Related Diseases

Diseases Alias
Progesterone Resistance

Pseudocorpus Luteum Insufficiency
Endometriosis Of Ovary

Ovarian Endometriosis
Asperger Syndrome

Asperger Disorder

Asperger Syndrome, Susceptibility To
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06395 HSD17B2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HSD17B2 VGNC VGNC:41805
Macaca mulatta HSD17B2 VGNC VGNC:99512
Bos taurus HSD17B2 VGNC VGNC:29973
Mus musculus HSD17B2 MGD MGI:1096386
Felis catus HSD17B2 VGNC VGNC:67657
Rattus norvegicus HSD17B2 RGD RGD:621803