S100A7A - S100 calcium binding protein A7A Gene

Homo sapiens

Also known as NICE2; NICE-2; S100A15; S100A7f; S100A7L1

Gene ID: 338324 | Gene type: protein coding

About S100A7A

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,416,520-153,423,222 (from NCBI)

This gene has 3 transcripts (splice variants), 285 orthologues and 21 paralogues. Low expression observed in reference dataset.

Summary

Enables protein self-association. Predicted to act upstream of or within inflammatory response. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

S100A7A Products(1)

mRNA	Protein	Name
NM_176823.4	NP_789793.1	protein S100-A7A

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IDA IDA: Inferred from direct assay	21148126	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

S100A7A Protein Structure

S_100

0
101 a.a.

Protein Preferred Names

Protein Names

protein S100-A7A

S100 calcium-binding protein A15

S100A7A Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	S100A7A	Q86SG5	S100A7L2	Homo sapiens	Q5SY68	MAPPIT	32296183
Intra	S100A7A	Q86SG5	S100A7L2	Homo sapiens	Q5SY68	Y2H Array	32296183
Intra	S100A7A	Q86SG5	S100A7L2	Homo sapiens	Q5SY68	Y2H Prey Pooling	32296183
Intra	S100A7A	Q86SG5	CLVS2	Homo sapiens	Q5SYC1	Y2H Prey Pooling	32296183
Intra	S100A7A	Q86SG5	CLVS2	Homo sapiens	Q5SYC1	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant S100A7A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71837	S100A7A Protein, Human (P.pastoris, His)	Q86SG5 (S2-Q101)	≥95%

Related Diseases

Diseases

Alias

Psoriasis

Macular Degeneration, Age-Related, 13

Age Related Macular Degeneration 13	ARMD13
Macular Degeneration, Age-Related, 13, Susceptibility To	Macular Degeneration, Age-Related, Type 13

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12384	S100A7A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	S100A7A	RGD	RGD:1593779
Mus musculus	S100A7A	MGD	MGI:2687194

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