2. Gene
  3. Tigit - T cell immunoreceptor with Ig and ITIM domains Gene

Tigit - T cell immunoreceptor with Ig and ITIM domains Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1563191

Gene ID: 363784 | Gene type: protein coding

About Tigit

Summary

Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in negative regulation of T cell activation; negative regulation of interleukin-12 production; and positive regulation of interleukin-10 production. Predicted to be integral component of membrane. Predicted to be active in cell surface. Orthologous to human TIGIT (T cell immunoreceptor with Ig and ITIM domains). [provided by Alliance of Genome Resources, Apr 2022]

Tigit Products(1)

mRNA Protein Name
XM_008768765.2 XP_008766987.1 T-cell immunoreceptor with Ig and ITIM domains
Protein Preferred Names Protein Names

T-cell immunoreceptor with Ig and ITIM domains

Recombinant Tigit Proteins

Cat. No. Product Name Accession Purity
HY-P74513 TIGIT Protein, Rat (HEK293, Fc) XP_008766987 (A17-A137) ≥95%

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0070A Liothyronine Activator 99.82% Yes
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14524 TIGIT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990704 Rilvegostomig / Unkown
HY-P990960 Lucorafusp alfa / Unkown
HY-P990746 Lancastotug Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tigit NCBI NCBI:201633
Macaca fascicularis Tigit NCBI NCBI:102121588
Mus musculus Tigit NCBI NCBI:100043314
Leporidae Tigit NCBI