2. Inhibitory Antibodies
  3. Tiragolumab

Tiragolumab  (Synonyms: MTIG-7192A; RG-6058)

Cat. No.: HY-P9986 Purity: ≥95.0%
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Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab (HY-P9904), may be effective against multiple solid malignancies-most notably non-small cell lung cancer (NSCLC).

For research use only. We do not sell to patients.

CAS No. : 1918185-84-8

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1 mg USD 180 In-stock
5 mg USD 540 In-stock
10 mg USD 870 In-stock
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Based on 1 publication(s) in Google Scholar

Tiragolumab Related Antibodies

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Description

Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab (HY-P9904), may be effective against multiple solid malignancies-most notably non-small cell lung cancer (NSCLC)[1][2].

IC50 & Target

TIGIT[1]
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tiragolumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Tiragolumab has a significant ADCP effect on CHO-K1/TIGIT cells in a dose-dependent manner.The EC50 for this effect is 189.43 ng/mL.
Purity & Documentation
References
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Tiragolumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tiragolumab1918185-84-8MTIG-7192A RG-6058RG6058RG 6058RG-6058Othersimmune checkpointT-cell immunoglobulinITIM domainTIGITsolid malignanciesNSCLCInhibitorinhibitorinhibit

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