2. Gene
  3. TMEM205 - transmembrane protein 205 Gene

TMEM205 - transmembrane protein 205 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UNQ501

Gene ID: 374882 | Gene type: protein coding

About TMEM205

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:11,342,778-11,346,492 (from NCBI)

This gene has 16 transcripts (splice variants) and 164 orthologues. Ubiquitous expression in liver (RPKM 32.8), thyroid (RPKM 28.6) and 25 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM205 Products(6)

mRNA Protein Name
NM_001145416.2 NP_001138888.1 transmembrane protein 205
NM_001321112.2 NP_001308041.1 transmembrane protein 205
NM_001321113.2 NP_001308042.1 transmembrane protein 205
NM_001321114.2 NP_001308043.1 transmembrane protein 205
NM_033408.4 NP_212133.1 transmembrane protein 205
NM_198536.3 NP_940938.1 transmembrane protein 205
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM205 Protein Structure

DUF4149

DUF4149: Domain of unknown function (DUF4149) (18 - 114)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

transmembrane protein 205

MBC3205

TMEM205 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TMEM205 Q6UW68 VRK2 Homo sapiens Q86Y07
Validated Y2H
32296183
Intra
TMEM205 Q6UW68 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra
TMEM205 Q6UW68 ARL6IP6 Homo sapiens Q8N6S5
Validated Y2H
32296183
Intra
TMEM205 Q6UW68 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra
TMEM205 Q6UW68 STX8 Homo sapiens Q9UNK0
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14694 TMEM205 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMEM205 VGNC VGNC:47524
Mus musculus TMEM205 MGD MGI:3045495
Macaca mulatta TMEM205 VGNC VGNC:79818
Felis catus TMEM205 VGNC VGNC:102719
Bos taurus TMEM205 VGNC VGNC:36027
Rattus norvegicus TMEM205 RGD RGD:1563250