TMEM140 - transmembrane protein 140 Gene

Homo sapiens

Gene ID: 55281 | Gene type: protein coding

About TMEM140

This gene has 2 transcripts (splice variants) and 107 orthologues. Ubiquitous expression in fat (RPKM 20.1), lung (RPKM 18.2) and 25 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM140 Products(1)

mRNA	Protein	Name
NM_018295.5	NP_060765.4	transmembrane protein 140

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM140 Protein Structure

TM140

0
100
185 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 140

TMEM140 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TMEM140	Q9NV12	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	TMEM140	Q9NV12	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TMEM182	Homo sapiens	Q6ZP80	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TMEM182	Homo sapiens	Q6ZP80	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	RMDN3	Homo sapiens	Q96TC7	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	RMDN3	Homo sapiens	Q96TC7	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MFF	Homo sapiens	Q9GZY8-5	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MFF	Homo sapiens	Q9GZY8-5	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CLEC17A	Homo sapiens	Q6ZS10	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CLEC17A	Homo sapiens	Q6ZS10	Y2H Array	32296183
Intra	TMEM140	Q9NV12	STOM	Homo sapiens	P27105	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	STOM	Homo sapiens	P27105	Y2H Array	32296183
Intra	TMEM140	Q9NV12	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	TMEM140	Q9NV12	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TSPO2	Homo sapiens	Q5TGU0	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TSPO2	Homo sapiens	Q5TGU0	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	MS4A3	Homo sapiens	Q96HJ5	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	MS4A3	Homo sapiens	Q96HJ5	Y2H Array	32296183
Intra	TMEM140	Q9NV12	ASGR2	Homo sapiens	P07307-3	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	ASGR2	Homo sapiens	P07307-3	Y2H Array	32296183
Intra	TMEM140	Q9NV12	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TMEM207	Homo sapiens	Q6UWW9	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TMEM207	Homo sapiens	Q6UWW9	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CD22	Homo sapiens	P20273-5	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CD22	Homo sapiens	P20273-5	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	TMEM140	Q9NV12	SCN3B	Homo sapiens	Q9NY72	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SCN3B	Homo sapiens	Q9NY72	Validated Y2H	32296183
Intra	TMEM140	Q9NV12	SCN3B	Homo sapiens	Q9NY72	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CLRN1	Homo sapiens	P58418	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CLRN1	Homo sapiens	P58418	Y2H Array	32296183
Intra	TMEM140	Q9NV12	KCNJ8	Homo sapiens	Q15842	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	KCNJ8	Homo sapiens	Q15842	Y2H Array	32296183
Intra	TMEM140	Q9NV12	SPACA1	Homo sapiens	Q9HBV2	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SPACA1	Homo sapiens	Q9HBV2	Y2H Array	32296183
Intra	TMEM140	Q9NV12	SHISAL1	Homo sapiens	Q3SXP7	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SHISAL1	Homo sapiens	Q3SXP7	Y2H Array	32296183
Intra	TMEM140	Q9NV12	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
Intra	TMEM140	Q9NV12	GPR42	Homo sapiens	O15529	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	GPR42	Homo sapiens	O15529	Y2H Array	32296183
Intra	TMEM140	Q9NV12	LY6E	Homo sapiens	Q16553	Y2H Array	32296183
Intra	TMEM140	Q9NV12	LY6E	Homo sapiens	Q16553	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
Intra	TMEM140	Q9NV12	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	MILR1	Homo sapiens	Q7Z6M3	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MILR1	Homo sapiens	Q7Z6M3	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CLDN5	Homo sapiens	O00501	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CLDN5	Homo sapiens	O00501	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	FAM210B	Homo sapiens	Q96KR6	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	FAM210B	Homo sapiens	Q96KR6	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TEX29	Homo sapiens	Q8N6K0	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TEX29	Homo sapiens	Q8N6K0	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CGRRF1	Homo sapiens	Q99675	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CGRRF1	Homo sapiens	Q99675	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TSPAN12	Homo sapiens	O95859	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TSPAN12	Homo sapiens	O95859	Y2H Array	32296183
Intra	TMEM140	Q9NV12	APH1A	Homo sapiens	Q96BI3	Y2H Array	32296183
Intra	TMEM140	Q9NV12	APH1A	Homo sapiens	Q96BI3	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SLC39A9	Homo sapiens	Q9NUM3	Y2H Array	32296183
Intra	TMEM140	Q9NV12	SLC39A9	Homo sapiens	Q9NUM3	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	HHLA2	Homo sapiens	Q9UM44	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	HHLA2	Homo sapiens	Q9UM44	Validated Y2H	32296183
Intra	TMEM140	Q9NV12	HHLA2	Homo sapiens	Q9UM44	Y2H Array	32296183
Intra	TMEM140	Q9NV12	IFNGR2	Homo sapiens	P38484	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	IFNGR2	Homo sapiens	P38484	Y2H Array	32296183
Intra	TMEM140	Q9NV12	EBP	Homo sapiens	Q15125	Y2H Array	32296183
Intra	TMEM140	Q9NV12	EBP	Homo sapiens	Q15125	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TMEM205	Homo sapiens	Q6UW68	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TMEM205	Homo sapiens	Q6UW68	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	TMEM140	Q9NV12	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CD53	Homo sapiens	P19397	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CD53	Homo sapiens	P19397	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SIT1	Homo sapiens	Q9Y3P8	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	SIT1	Homo sapiens	Q9Y3P8	Validated Y2H	32296183
Intra	TMEM140	Q9NV12	SIT1	Homo sapiens	Q9Y3P8	Y2H Array	32296183
Intra	TMEM140	Q9NV12	GOLM1	Homo sapiens	Q8NBJ4	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	GOLM1	Homo sapiens	Q8NBJ4	Y2H Array	32296183
Intra	TMEM140	Q9NV12	SYNE4	Homo sapiens	Q8N205	Validated Y2H	25416956
Intra	TMEM140	Q9NV12	PDZK1IP1	Homo sapiens	Q13113	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	PDZK1IP1	Homo sapiens	Q13113	Y2H Array	32296183
Intra	TMEM140	Q9NV12	TMEM9	Homo sapiens	Q9P0T7	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	TMEM9	Homo sapiens	Q9P0T7	Validated Y2H	32296183
Intra	TMEM140	Q9NV12	TMEM9	Homo sapiens	Q9P0T7	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	MGST3	Homo sapiens	O14880	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CLDN7	Homo sapiens	O95471	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CLDN7	Homo sapiens	O95471	Y2H Array	32296183
Intra	TMEM140	Q9NV12	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	TMEM140	Q9NV12	CD79A	Homo sapiens	P11912	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MSMO1	Homo sapiens	Q15800	Y2H Array	32296183
Intra	TMEM140	Q9NV12	MSMO1	Homo sapiens	Q15800	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14668	TMEM140 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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