2. Gene
  3. Gipr - gastric inhibitory polypeptide receptor Gene

Gipr - gastric inhibitory polypeptide receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GIP-R; Gm160; Gm1081

Gene ID: 381853 | Gene type: protein coding

About Gipr

Summary

Predicted to enable G protein-coupled peptide receptor activity; gastric inhibitory peptide receptor activity; and glucagon family peptide binding activity. Acts upstream of or within endocrine pancreas development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in foregut-midgut junction; pancreas; and pancreas primordium. Human ortholog(s) of this gene implicated in cardiovascular system disease; diabetes mellitus; obesity; and type 2 diabetes mellitus. Orthologous to human GIPR (gastric inhibitory polypeptide receptor). [provided by Alliance of Genome Resources, Apr 2022]

Gipr Products(1)

mRNA Protein Name
NM_001080815.1 NP_001074284.1 gastric inhibitory polypeptide receptor precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables gastric inhibitory peptide receptor activity IDA
IDA: Inferred from direct assay
17971513 MGI
Biological Process GO Annotation Evidence Reference Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
15111503 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
23099862 MGI
acts upstream of or within endocrine pancreas development IMP
IMP: Inferred from mutant phenotype
21270265 MGI
involved in positive regulation of insulin secretion IGI
IGI: Inferred from genetic interaction
15111503 MGI
involved in positive regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
23099862 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
17971513 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gastric inhibitory polypeptide receptor

glucose-dependent insulinotropic polypeptide receptor

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-P3506 Retatrutide Agonist 99.96% Phase 3
HY-P3506A Retatrutide TFA Agonist 99.31% Phase 3
HY-P3506B Retatrutide acetate Agonist / Phase 3
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990047 Maridebart Inhibitor 95.14% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P3584A (Pro3) GIP, human TFA 99.79% Unkown
HY-P10302A GLP-1R/GIPR agonist-1 (soduim) Agonist 96.55% Unkown
HY-P10302 GLP-1R/GIPR agonist-1 Agonist / Unkown
HY-P3584 (Pro3) GIP, human Agonist 99.79% Unkown
HY-P10271 RG7697 Agonist / Unkown
HY-RS05437 GIPR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gipr NCBI NCBI:2696
Macaca fascicularis Gipr NCBI NCBI:102123760
Rattus norvegicus Gipr NCBI NCBI:25024