GOLGA7B - golgin A7 family member B Gene

Homo sapiens

Also known as C10orf132; C10orf133; bA459F3.4; bA451M19.3

Gene ID: 401647 | Gene type: protein coding

About GOLGA7B

Cytogenetic location: 10q24.2 Genomic coordinates (GRCh38): 10:97,849,843-97,871,578 (from NCBI)

This gene has 3 transcripts (splice variants), 268 orthologues and 1 paralogue. Biased expression in brain (RPKM 7.2), skin (RPKM 7.1) and 11 other tissues.

Summary

Enables Enzyme binding activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

GOLGA7B Products(1)

mRNA	Protein	Name
NM_001010917.3	NP_001010917.1	golgin subfamily A member 7B

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	31402609	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	31402609	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GOLGA7B Protein Structure

Erf4

0
100
167 a.a.

Protein Preferred Names

Protein Names

golgin subfamily A member 7B

golgi autoantigen, golgin subfamily a, 7B

GOLGA7B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GOLGA7B	Q2TAP0	ZNF564	Homo sapiens	Q8TBZ8	Validated Y2H	32296183
Intra	GOLGA7B	Q2TAP0	ZDHHC15	Homo sapiens	Q96MV8	Validated Y2H	32296183
Intra	GOLGA7B	Q2TAP0	ZDHHC15	Homo sapiens	Q96MV8	Y2H Array	32296183
Intra	GOLGA7B	Q2TAP0	ZDHHC15	Homo sapiens	Q96MV8	Y2H Prey Pooling	32296183
Intra	GOLGA7B	Q2TAP0	ZDHHC5	Homo sapiens	Q9C0B5	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Alzheimer Disease 18

AD18	Alzheimer'S Disease 18
Alzheimer Disease 18, Late-Onset	Alzheimer Disease 18, Susceptibility To
Alzheimer'S Disease 18, Late Onset	Alzheimer Disease 18 Late-Onset
Alzheimer Disease, Susceptibility To, Type 18

Hydrolethalus Syndrome 1

Hydrolethalus Syndrome	HLS1
Salonen-Herva-Norio Syndrome	Hls
Hydrolethalus	Hydrolethalus Syndrome, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05589	GOLGA7B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GOLGA7B	VGNC	VGNC:52993
Macaca mulatta	GOLGA7B	VGNC	VGNC:106053
Bos taurus	GOLGA7B	VGNC	VGNC:29488
Mus musculus	GOLGA7B	MGD	MGI:1918396
Rattus norvegicus	GOLGA7B	RGD	RGD:1583839

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