2. Gene
  3. NPTX1 - neuronal pentraxin 1 Gene

NPTX1 - neuronal pentraxin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NP1

Gene ID: 4884 | Gene type: protein coding

About NPTX1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:80,466,834-80,476,607 (from NCBI)

This gene has 5 transcripts (splice variants), 264 orthologues and 5 paralogues. Biased expression in brain (RPKM 51.6) and adrenal (RPKM 2.1).

Summary

NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]

NPTX1 Products(1)

mRNA Protein Name
NM_002522.4 NP_002513.2 neuronal pentraxin-1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27986928 GOA
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27986928 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NPTX1 Protein Structure

Pentaxin

Pentaxin: Pentaxin family (232 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 432 a.a.
Protein Preferred Names Protein Names

neuronal pentraxin-1

NP-I

Recombinant NPTX1 Proteins

Cat. No. Product Name Accession Purity
HY-P71169 NPTX1 Protein, Human (HEK293, His) Q15818 (Q23-N432) ≥95%

Related Diseases

Diseases Alias
Wallerian Degeneration

Wallerian Degeneration Of The Pyramidal Tract
Central Precocious Puberty

Cpp

Gonadotropin-Dependant Precocious Puberty

Gonadotropin-Dependent Precocious Puberty

Precocious Puberty, Central
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09505 NPTX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NPTX1 VGNC VGNC:43933
Macaca mulatta NPTX1 VGNC VGNC:75391
Felis catus NPTX1 VGNC VGNC:99309
Rattus norvegicus NPTX1 RGD RGD:628894
Bos taurus NPTX1 VGNC VGNC:32218
Mus musculus NPTX1 MGD MGI:107811
Others NPTX1 NCBI