2. Gene
  3. Uchl3 - ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) Gene

Uchl3 - ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 50933 | Gene type: protein coding

About Uchl3

Summary

Enables Deubiquitinase activity. Involved in cellular response to Insulin stimulus; positive regulation of fat cell differentiation; and protein catabolic process. Acts upstream of or within several processes, including adult walking behavior; eating behavior; and protein deubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including embryo ectoderm; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human UCHL3 (ubiquitin C-terminal hydrolase L3). [provided by Alliance of Genome Resources, Apr 2022]

Uchl3 Products(1)

mRNA Protein Name
NM_016723.2 NP_057932.2 ubiquitin carboxyl-terminal hydrolase isozyme L3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables deubiquitinase activity IDA
IDA: Inferred from direct assay
26609154 MGI
enables peptidase activity IDA
IDA: Inferred from direct assay
21762696 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adult walking behavior IGI
IGI: Inferred from genetic interaction
11555633 MGI
involved in cellular response to insulin stimulus IDA
IDA: Inferred from direct assay
19837878 MGI
acts upstream of or within eating behavior IGI
IGI: Inferred from genetic interaction
11555633 MGI
involved in positive regulation of fat cell differentiation IDA
IDA: Inferred from direct assay
19837878 MGI
involved in protein catabolic process IDA
IDA: Inferred from direct assay
21762696 MGI
acts upstream of or within protein deubiquitination IDA
IDA: Inferred from direct assay
26609154 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21052544 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase isozyme L3

UCH-L3

ubiquitin thioesterase L3

ubiquitin thiolesterase

Recombinant Uchl3 Proteins

Cat. No. Product Name Accession Purity
HY-P76119 UCHL3 Protein, Mouse (His) Q9JKB1 (E2-A230) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18637 LDN-57444 98.93% Unkown
HY-133118 6RK73 Inhibitor 99.52% Unkown
HY-18638 TCID Inhibitor 99.87% Unkown
HY-149230 USP28-IN-4 Inhibitor 99.35% Unkown
HY-149229 USP28-IN-3 Inhibitor 98.26% Unkown
HY-149228 USP28-IN-2 Inhibitor / Unkown
HY-RS15401 UCHL3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uchl3 NCBI NCBI:7347
Rattus norvegicus Uchl3 NCBI NCBI:498560