GDE1 - glycerophosphodiester phosphodiesterase 1 Gene

Homo sapiens

Also known as MIR16; 363E6.2

Gene ID: 51573 | Gene type: protein coding

About GDE1

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:19,501,693-19,522,098 (from NCBI)

This gene has 5 transcripts (splice variants), 250 orthologues and 5 paralogues. Ubiquitous expression in colon (RPKM 28.1), fat (RPKM 25.8) and 25 other tissues.

Summary

Predicted to enable glycerophosphodiester phosphodiesterase activity; glycerophosphoinositol glycerophosphodiesterase activity; and lysophospholipase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GDE1 Products(3)

mRNA	Protein	Name
NM_001324066.2	NP_001310995.1	glycerophosphodiester phosphodiesterase 1 isoform 2
NM_001324067.2	NP_001310996.1	glycerophosphodiester phosphodiesterase 1 isoform 3
NM_016641.4	NP_057725.1	glycerophosphodiester phosphodiesterase 1 isoform 1

GDE1 Protein Structure

GDPD

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

glycerophosphodiester phosphodiesterase 1

RGS16-interacting membrane protein

GDE1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GDE1	Q9NZC3	SLC10A1	Homo sapiens	Q14973	Y2H Prey Pooling	32296183
Intra	GDE1	Q9NZC3	SLC10A1	Homo sapiens	Q14973	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Serine Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05348	GDE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W127407	Glycerophospho-N-arachidonoyl ethanolamine		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GDE1	MGD	MGI:1891827
Canis familiaris	GDE1	VGNC	VGNC:103677
Rattus norvegicus	GDE1	RGD	RGD:621788
Macaca mulatta	GDE1	VGNC	VGNC:72807
Felis catus	GDE1	VGNC	VGNC:62501
Bos taurus	GDE1	VGNC	VGNC:29298

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