1. Gene
  2. TAF9B - TATA-box binding protein associated factor 9b Gene

TAF9B - TATA-box binding protein associated factor 9b Gene

Homo sapiens

Also known as DN7; DN-7; TAF9L; TAFII31L; TFIID-31

Gene ID: 51616 | Gene type: protein coding

About TAF9B

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:78,129,748-78,139,650 (from NCBI)

This gene has 2 transcripts (splice variants), 93 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 16.6), endometrium (RPKM 13.8) and 25 other tissues.

Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008]

TAF9B Products(1)

mRNA Protein Name
NM_015975.5 NP_057059.2 transcription initiation factor TFIID subunit 9B

TAF9B Protein Structure

TFIID-31kDa

TFIID-31kDa: Transcription initiation factor IID, 31kD subunit (2 - 130)

  • 0
  • 100
  • 200
  • 251 a.a.
Protein Preferred Names Protein Names

transcription initiation factor TFIID subunit 9B

TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa

Related Diseases

Diseases Alias
Syndromic X-Linked Intellectual Disability Siderius Type

Mrxssd

Siderius-Hamel Syndrome

Siderius X-Linked Mental Retardation Syndrome

Plantar Fasciitis

Fasciitis, Plantar

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus TAF9B VGNC VGNC:65938
Mus musculus TAF9B MGD MGI:3039562
Canis familiaris TAF9B VGNC VGNC:47091
Macaca mulatta TAF9B VGNC VGNC:78150
Rattus norvegicus TAF9B RGD RGD:621116
Bos taurus TAF9B VGNC VGNC:35583