2. Gene
  3. SARAF - store-operated calcium entry associated regulatory factor Gene

SARAF - store-operated calcium entry associated regulatory factor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as XTP3; FOAP-7; TMEM66; HSPC035

Gene ID: 51669 | Gene type: protein coding

About SARAF

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:30,063,003-30,083,208 (from NCBI)

This gene has 14 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in brain (RPKM 148.3), adrenal (RPKM 121.7) and 25 other tissues.

Summary

Involved in regulation of store-operated calcium entry. Located in endoplasmic reticulum and endoplasmic reticulum-plasma membrane contact site. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

SARAF Products(2)

mRNA Protein Name
NM_001284239.1 NP_001271168.1 store-operated calcium entry-associated regulatory factor isoform 2
NM_016127.6 NP_057211.4 store-operated calcium entry-associated regulatory factor isoform 1 precursor

SARAF Protein Structure

SARAF

SARAF: SOCE-associated regulatory factor of calcium homoeostasis (20 - 339)

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  • 339 a.a.
Protein Preferred Names Protein Names

store-operated calcium entry-associated regulatory factor

HBV X-transactivated gene 3 protein

Related Diseases

Diseases Alias
Stormorken Syndrome

Thrombocytopathy, Asplenia, And Miosis

Stormorken-Sjaastad-Langslet Syndrome

STRMK

York Platelet Syndrome

Yps

Thrombocytopathy, Asplenia And Miosis

Thrombocytopathy Asplenia Miosis

Thrombocytopathy-Asplenia-Miosis Syndrome

Miosis Disorder
Robinow Syndrome, Autosomal Dominant 2

Autosomal Dominant Robinow Syndrome 2

DRS2

Robinow, Autosomal Dominant Syndrome, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12444 SARAF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SARAF RGD RGD:1303011
Mus musculus SARAF MGD MGI:1915137
Macaca mulatta SARAF VGNC VGNC:77118
Bos taurus SARAF VGNC VGNC:34288
Felis catus SARAF VGNC VGNC:79998
Canis familiaris SARAF VGNC VGNC:45866