2. Gene
  3. Tslp - thymic stromal lymphopoietin Gene

Tslp - thymic stromal lymphopoietin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 53603 | Gene type: protein coding

About Tslp

Summary

Enables cytokine activity. Predicted to be involved in several processes, including defense response to Other organism; positive regulation of cytokine production; and positive regulation of signal transduction. Predicted to be located in extracellular region. Is expressed in ductus deferens; epididymis; ileum; and testis. Used to study atopic dermatitis; autoimmune hemolytic anemia; cryoglobulinemia; and membranoproliferative glomerulonephritis. Orthologous to human TSLP (thymic stromal lymphopoietin). [provided by Alliance of Genome Resources, Apr 2022]

Tslp Products(1)

mRNA Protein Name
NM_021367.2 NP_067342.1 thymic stromal lymphopoietin precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cytokine activity IDA
IDA: Inferred from direct assay
10974033 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24632570 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in extracellular space IDA
IDA: Inferred from direct assay
28811323 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thymic stromal lymphopoietin

thymic stroma-derived lymphopoietin

Tslp Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Tslp Q9JIE6 Crlf2 Mus musculus Q8CII9
GMS
24632570
Intra
Tslp Q9JIE6 Crlf2 Mus musculus Q8CII9
Light Scattering
24632570
Intra
Tslp Q9JIE6 Crlf2 Mus musculus Q8CII9
ITC
24632570
Intra
Tslp Q9JIE6 Crlf2 Mus musculus Q8CII9
SPR
24632570
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Tslp Proteins

Cat. No. Product Name Accession Purity
HY-P70626 TSLP Protein, Mouse (HEK293, Fc) Q9JIE6 (Y20-E140) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150207 RBN-3143 Inhibitor 99.24% Unkown
HY-RS15153 TSLP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99366A Tezepelumab (anti-TSLP) 98.64% Unkown
HY-P990748 Lunsekimig / Unkown
HY-P990906 Bosakitug / Unkown
HY-P990933 Ocankitug / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tslp NCBI NCBI:85480
Macaca fascicularis Tslp NCBI NCBI:102119254