1. Gene
  2. APBB1IP - amyloid beta precursor protein binding family B member 1 interacting protein Gene

APBB1IP - amyloid beta precursor protein binding family B member 1 interacting protein Gene

Homo sapiens

Also known as RIAM; INAG1; PREL1; RARP1

Gene ID: 54518 | Gene type: protein coding

About APBB1IP

Cytogenetic location: 10p12.1 Genomic coordinates (GRCh38): 10:26,438,341-26,567,803 (from NCBI)

This gene has 3 transcripts (splice variants), 257 orthologues and 4 paralogues. Broad expression in appendix (RPKM 24.2), spleen (RPKM 22.5) and 16 other tissues.

Summary

Predicted to be involved in signal transduction. Predicted to act upstream of or within T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and positive regulation of cell adhesion. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

APBB1IP Products(1)

mRNA Protein Name
NM_019043.4 NP_061916.3 amyloid beta A4 precursor protein-binding family B member 1-interacting protein

APBB1IP Protein Structure

RA

RA: Ras association (RalGDS/AF-6) domain (178 - 262)

PH

PH: PH domain (312 - 416)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
Protein Preferred Names Protein Names

amyloid beta A4 precursor protein-binding family B member 1-interacting protein

APBB1-interacting protein 1

Related Diseases

Diseases Alias
Leukocyte Adhesion Deficiency, Type I

Leukocyte Adhesion Deficiency

Leukocyte Adhesion Deficiency 1

LAD1

Lad

Lymphocyte Function-Associated Antigen 1 Immunodeficiency

Leukocyte Adhesion Deficiency Type I

Leukocyte Adhesion Deficiency Type 1

Linear Iga Bullous Dermatosis

Linear Iga Dermatosis

Leukocyte-Adhesion Deficiency Syndrome

Lfa1 Immunodeficiency

Congenital Leukocyte Adherence Deficiency

Lad-I

Linear Iga Disease

Leukocyte Adhesion Deficiency Syndrome

Lad 1

Lfa 1 Immunodeficiency

Linear Immunoglobulin A Dermatosis

Leucocyte Adhesion Deficiency Type 1

Leukocyte Adhesion Molecule Deficiency Type 1

Leukocyte Adhesion Deficiency, Type Iii

Leukocyte Adhesion Deficiency 3

LAD3

Leukocyte Adhesion Deficiency 1 Variant

Lad1v

Integrin Activation Deficiency Disease

Iadd

Leukocyte Adhesion Deficiency Type Iii

Lad1 Variant

Lad-1 Variant

Lad-Iii

Leukocyte Adhesion Deficiency-1 Variant

Leukocyte Adhesion Deficiency Type 1

Rocky Mountain Spotted Fever

Brazillian Spotted

Choix

Exanthematic Typhus Of Sao Paulo

Fiebre Maculosa

Fiebre Manchada

Sao Paulo Typhus

So Paulo Fever

Tick Typhus

Tobia Fever

Rmsf

Typhus, Tick

Combined Immunodeficiency

Combined T Cell And B Cell Immunodeficiency

Congenital Combined Immunodeficiency

Syndrome With Combined Immunodeficiency

Combined T And B Cell Immunodeficiency

Combined Immunity Deficiency

Combined Immunodeficiency Syndrome

Combined T-Cell And B-Cell Immunodeficiency

Lymphopenic Agammaglobulinaemia

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta APBB1IP VGNC VGNC:100295
Canis familiaris APBB1IP VGNC VGNC:37978
Rattus norvegicus APBB1IP RGD RGD:1304795
Felis catus APBB1IP VGNC VGNC:59844
Bos taurus APBB1IP VGNC VGNC:26004
Mus musculus APBB1IP MGD MGI:1861354