OCIAD1 - OCIA domain containing 1 Gene

Homo sapiens

Also known as OCIA; ASRIJ; TPA018

Gene ID: 54940 | Gene type: protein coding

About OCIAD1

Cytogenetic location: 4p11 Genomic coordinates (GRCh38): 4:48,805,156-48,861,815 (from NCBI)

This gene has 28 transcripts (splice variants), 138 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 53.3), brain (RPKM 50.0) and 25 other tissues.

Summary

Predicted to be involved in several processes, including hematopoietic stem cell homeostasis; positive regulation of receptor signaling pathway via JAK-STAT; and regulation of stem cell differentiation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

OCIAD1 Products(6)

mRNA	Protein	Name
NM_001079839.3	NP_001073308.1	OCIA domain-containing protein 1 isoform 1
NM_001079840.3	NP_001073309.1	OCIA domain-containing protein 1 isoform 2
NM_001079841.3	NP_001073310.1	OCIA domain-containing protein 1 isoform 3
NM_001079842.3	NP_001073311.2	OCIA domain-containing protein 1 isoform 2
NM_001168254.2	NP_001161726.1	OCIA domain-containing protein 1 isoform 4
NM_017830.4	NP_060300.1	OCIA domain-containing protein 1 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20195357	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OCIAD1 Protein Structure

OCIA

0
100
200
245 a.a.

Protein Preferred Names

Protein Names

OCIA domain-containing protein 1

ovarian cancer immunoreactive antigen domain containing 1

OCIAD1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	OCIAD1	Q9NX40	SLC30A3	Homo sapiens	Q99726	Anti Tag CoIP	33961781
Intra	OCIAD1	Q9NX40	MMD	Homo sapiens	Q15546	Y2H Array	32296183
Intra	OCIAD1	Q9NX40	MMD	Homo sapiens	Q15546	Y2H Prey Pooling	32296183
Intra	OCIAD1	Q9NX40	FKBP7	Homo sapiens	Q9Y680	Y2H Prey Pooling	32296183
Intra	OCIAD1	Q9NX40	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	32296183
Intra	OCIAD1	Q9NX40	FKBP7	Homo sapiens	Q9Y680	Y2H Array	32296183
Intra	OCIAD1	Q9NX40	ATF7	Homo sapiens	P17544	TAP	20195357

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09741	OCIAD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	OCIAD1	VGNC	VGNC:53769
Canis familiaris	OCIAD1	VGNC	VGNC:44092
Felis catus	OCIAD1	VGNC	VGNC:63946
Mus musculus	OCIAD1	MGD	MGI:1915345
Rattus norvegicus	OCIAD1	RGD	RGD:1359549
Macaca mulatta	OCIAD1	VGNC	VGNC:75409

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