2. Gene
  3. RADX - RPA1 related single stranded DNA binding protein, X-linked Gene

RADX - RPA1 related single stranded DNA binding protein, X-linked Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CXorf57

Gene ID: 55086 | Gene type: protein coding

About RADX

This gene has 6 transcripts (splice variants) and 188 orthologues. Broad expression in adrenal (RPKM 4.5), ovary (RPKM 4.0) and 24 other tissues.

Summary

Enables single-stranded DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in nuclear speck and replication fork. [provided by Alliance of Genome Resources, Apr 2022]

RADX Products(2)

mRNA Protein Name
NM_001184782.2 NP_001171711.1 RPA-related protein RADX isoform 2
NM_018015.6 NP_060485.4 RPA-related protein RADX isoform 1
Protein Preferred Names Protein Names

RPA-related protein RADX

RPA-related and RAD51-antagonist, X-chromosome

Related Diseases

Diseases Alias
Schimke Immunoosseous Dysplasia

Schimke Immuno-Osseous Dysplasia

SIOD

Immunoosseous Dysplasia, Schimke Type

Schimke Syndrome

Immunoosseous Dysplasia Schimke Type

Spondyloepiphyseal Dysplasia - Nephrotic Syndrome

Spondyloepiphyseal Dysplasia Nephrotic Syndrome

Spondyloepiphyseal Dysplasia-Nephrotic Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13058B (R)-ADX-47273 Modulator 99.00% Unkown
HY-RS11616 RADX Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RADX RGD RGD:1589413
Canis familiaris RADX VGNC VGNC:52594
Mus musculus RADX MGD MGI:2147848
Bos taurus RADX VGNC VGNC:52760