LARP1B - La ribonucleoprotein 1B Gene

Homo sapiens

Also known as LARP2

Gene ID: 55132 | Gene type: protein coding

About LARP1B

This gene has 15 transcripts (splice variants), 218 orthologues and 6 paralogues. Broad expression in testis (RPKM 13.1), liver (RPKM 5.0) and 25 other tissues.

Summary

This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent Amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]

LARP1B Products(6)

mRNA	Protein	Name
NM_001278604.2	NP_001265533.1	la-related protein 1B isoform 4
NM_001350531.2	NP_001337460.1	la-related protein 1B isoform 5
NM_001410786.1	NP_001397715.1	la-related protein 1B isoform 6
NM_018078.4	NP_060548.2	la-related protein 1B isoform 1
NM_032239.4	NP_115615.2	la-related protein 1B isoform 3
NM_178043.3	NP_835144.1	la-related protein 1B isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LARP1B Protein Structure

0
200
400
600
800
914 a.a.

Protein Preferred Names

Protein Names

la-related protein 1B

La ribonucleoprotein domain family member 1B

LARP1B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	LARP1B	Q659C4	KIF2A	Homo sapiens	O00139	Y2H Prey Pooling	25416956
Intra	LARP1B	Q659C4	KIF2A	Homo sapiens	O00139	Validated Y2H	25416956
Intra	LARP1B	Q659C4	TRIM69	Homo sapiens	Q86WT6	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07527	LARP1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LARP1B	MGD	MGI:1914604
Bos taurus	LARP1B	VGNC	VGNC:30791
Canis familiaris	LARP1B	VGNC	VGNC:42588
Rattus norvegicus	LARP1B	RGD	RGD:1307509
Macaca mulatta	LARP1B	VGNC	VGNC:74115
Felis catus	LARP1B	VGNC	VGNC:82486

Name
Email *

	Sorry, but the email address you supplied was invalid.