2. Gene
  3. ABCF3 - ATP binding cassette subfamily F member 3 Gene

ABCF3 - ATP binding cassette subfamily F member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EST201864

Gene ID: 55324 | Gene type: protein coding

About ABCF3

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:184,186,199-184,194,005 (from NCBI)

This gene has 18 transcripts (splice variants), 207 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 33.9), testis (RPKM 16.2) and 25 other tissues.

Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays Antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

ABCF3 Products(4)

mRNA Protein Name
NM_001351298.2 NP_001338227.1 ATP-binding cassette sub-family F member 3 isoform 2
NM_001351299.2 NP_001338228.1 ATP-binding cassette sub-family F member 3 isoform 3
NM_001351300.2 NP_001338229.1 ATP-binding cassette sub-family F member 3 isoform 4
NM_018358.3 NP_060828.2 ATP-binding cassette sub-family F member 3 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABCF3 Protein Structure

ABC_tran

ABC_tran: ABC transporter (196 - 356)

ABC_tran_Xtn

ABC_tran_Xtn: ABC transporter (395 - 474)

ABC_tran

ABC_tran: ABC transporter (510 - 639)

  • 0
  • 200
  • 400
  • 600
  • 709 a.a.
Protein Preferred Names Protein Names

ATP-binding cassette sub-family F member 3

ATP-binding cassette, sub-family F (GCN20), member 3

ABCF3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ABCF3 Q9NUQ8 FCHSD2 Homo sapiens O94868
Y2H Prey Pooling
25416956
Intra
ABCF3 Q9NUQ8 FCHSD2 Homo sapiens O94868
Y2H Array
25416956
Intra
ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Validated Y2H
26871637
Intra
ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Y2H Array
26871637
Intra
ABCF3 Q9NUQ8 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
26871637
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00075 ABCF3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ABCF3 VGNC VGNC:68301
Canis familiaris ABCF3 VGNC VGNC:37451
Mus musculus ABCF3 MGD MGI:1351656
Rattus norvegicus ABCF3 RGD RGD:1310468
Bos taurus ABCF3 VGNC VGNC:25482
Macaca mulatta ABCF3 VGNC VGNC:69583
Others ABCF3 NCBI