Cxcl13 - chemokine (C-X-C motif) ligand 13 Gene

Mus musculus

Also known as BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik

Gene ID: 55985 | Gene type: protein coding

About Cxcl13

Summary

Enables CXCR5 Chemokine Receptor binding activity and chemokine activity. Involved in several processes, including B cell chemotaxis across high endothelial venule; activation of GTPase activity; and lymph node development. Located in extracellular space. Is expressed in Peyer's patch; aorta; central nervous system; and retina. Orthologous to human CXCL13 (C-X-C motif chemokine ligand 13). [provided by Alliance of Genome Resources, Apr 2022]

Cxcl13 Products(1)

mRNA	Protein	Name
NM_018866.2	NP_061354.1	C-X-C motif chemokine 13 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables CXCR5 chemokine receptor binding	IDA IDA: Inferred from direct assay	9463416	MGI
enables chemokine activity	IDA IDA: Inferred from direct assay	15972452	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in B cell chemotaxis	IMP IMP: Inferred from mutant phenotype	15972452	MGI
involved in B cell chemotaxis across high endothelial venule	IDA IDA: Inferred from direct assay	15972452	MGI
involved in activation of GTPase activity	IDA IDA: Inferred from direct assay	15972452	MGI
involved in lymph node development	IDA IDA: Inferred from direct assay	19783990	MGI
acts upstream of or within lymph node development	IMP IMP: Inferred from mutant phenotype	12732660	MGI
involved in lymphocyte chemotaxis across high endothelial venule	IMP IMP: Inferred from mutant phenotype	15972452	MGI
involved in positive regulation of cell-cell adhesion mediated by integrin	IDA IDA: Inferred from direct assay	15972452	MGI
involved in positive regulation of integrin activation	IDA IDA: Inferred from direct assay	15972452	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in extracellular space	IDA IDA: Inferred from direct assay	23460747	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

C-X-C motif chemokine 13

B lymphocyte chemoattractant	CXC chemokine BLC
small inducible cytokine subfamily B (Cys-X-Cys), member 13	small-inducible cytokine B13

Recombinant Cxcl13 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77911	BCA-1/CXCL13 Protein, Mouse (HEK293, His)	O55038 (I22-A109)	≥95%
HY-P77912	BCA-1/CXCL13 Protein, Mouse (HEK293, Fc)	O55038 (I22-A109)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03387	CXCL13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cxcl13	NCBI	NCBI:10563
Macaca fascicularis	Cxcl13	NCBI	NCBI:102123271
Susscrofa domestica	Cxcl13	NCBI
Rattus norvegicus	Cxcl13	NCBI	NCBI:498335

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