MTFR1L - mitochondrial fission regulator 1 like Gene

Homo sapiens

Also known as FAM54B; MST116; MSTP116; HYST1888

Gene ID: 56181 | Gene type: protein coding

About MTFR1L

This gene has 23 transcripts (splice variants), 209 orthologues and 2 paralogues. Ubiquitous expression in heart (RPKM 46.8), adrenal (RPKM 39.4) and 25 other tissues.

Summary

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MTFR1L Products(4)

mRNA	Protein	Name
NM_001099625.2	NP_001093095.1	mitochondrial fission regulator 1-like isoform a
NM_001099626.2	NP_001093096.1	mitochondrial fission regulator 1-like isoform a
NM_001099627.2	NP_001093097.1	mitochondrial fission regulator 1-like isoform b
NM_019557.6	NP_062457.3	mitochondrial fission regulator 1-like isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MTFR1L Protein Structure

Mito_fiss_reg

0
100
200
292 a.a.

Protein Preferred Names

Protein Names

mitochondrial fission regulator 1-like

family with sequence similarity 54 member B

MTFR1L Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	MTFR1L	Q9H019	ANKRD11	Homo sapiens	X5D778	Validated Y2H	32296183
Intra	MTFR1L	Q9H019	ARMC1	Homo sapiens	Q9NVT9	Y2H Array	31515488
Intra	MTFR1L	Q9H019	ARMC1	Homo sapiens	Q9NVT9	Y2H Prey Pooling	26871637
Intra	MTFR1L	Q9H019	ARMC1	Homo sapiens	Q9NVT9	Validated Y2H	26871637
Intra	MTFR1L	Q9H019	ARMC1	Homo sapiens	Q9NVT9	Y2H Array	26871637
Intra	MTFR1L	Q9H019	CNOT2	Homo sapiens	Q9NZN8	Validated Y2H	32296183
Intra	MTFR1L	Q9H019	MAGEA12	Homo sapiens	P43365	Y2H Prey Pooling	25416956
Intra	MTFR1L	Q9H019	MAGEA12	Homo sapiens	P43365	Y2H Prey Pooling	26871637
Intra	MTFR1L	Q9H019	MAGEA12	Homo sapiens	P43365	Validated Y2H	26871637
Intra	MTFR1L	Q9H019	MAGEA12	Homo sapiens	P43365	Y2H Array	25416956
Intra	MTFR1L	Q9H019	MAGEA12	Homo sapiens	P43365	Y2H Array	26871637
Intra	MTFR1L	Q9H019	AIRIM	Homo sapiens	Q9NX04	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Combined Oxidative Phosphorylation Deficiency 7

COXPD7	Combined Oxidative Phosphorylation Defect Type 7
Severe C12orf65-Related Combined Oxidative Phosphorylation Defect	Severe C12orf65-Related Coxpd
Combined Oxidative Phosphorylation Deficiency, Type 7

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08770	MTFR1L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MTFR1L	RGD	RGD:1305453
Felis catus	MTFR1L	VGNC	VGNC:80284
Macaca mulatta	MTFR1L	VGNC	VGNC:75036
Bos taurus	MTFR1L	VGNC	VGNC:31727
Mus musculus	MTFR1L	MGD	MGI:1924074
Canis familiaris	MTFR1L	VGNC	VGNC:43469

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