2. Gene
  3. Prpf40a - pre-mRNA processing factor 40A Gene

Prpf40a - pre-mRNA processing factor 40A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FBP11; Fnbp3; FBP-11; Fnbp11; 2810012K09Rik

Gene ID: 56194 | Gene type: protein coding

About Prpf40a

Summary

Enables proline-rich region binding activity. Predicted to be involved in several processes, including mRNA splicing, via spliceosome; regulation of cell shape; and regulation of cytokinesis. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nuclear matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PRPF40A (pre-mRNA processing factor 40 homolog A). [provided by Alliance of Genome Resources, Apr 2022]

Prpf40a Products(7)

mRNA Protein Name
NM_001371015.1 NP_001357944.1 pre-mRNA-processing factor 40 homolog A isoform 1
NM_001371016.1 NP_001357945.1 pre-mRNA-processing factor 40 homolog A isoform 3
NM_001371017.1 NP_001357946.1 pre-mRNA-processing factor 40 homolog A isoform 4
NM_001371018.1 NP_001357947.1 pre-mRNA-processing factor 40 homolog A isoform 5
NM_001371019.1 NP_001357948.1 pre-mRNA-processing factor 40 homolog A isoform 6
NM_001371020.1 NP_001357949.1 pre-mRNA-processing factor 40 homolog A isoform 7
NM_018785.3 NP_061255.2 pre-mRNA-processing factor 40 homolog A isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables proline-rich region binding IDA
IDA: Inferred from direct assay
17915251 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9171351 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nuclear matrix IDA
IDA: Inferred from direct assay
16391387 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11092755 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-processing factor 40 homolog A

PRP40 pre-mRNA processing factor 40 homolog A

formin binding protein 11

formin-binding protein 3

Prpf40a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Prpf40a Q9R1C7 AKAP8L Homo sapiens Q9ULX6
Y2H
16391387
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11212 PRPF40A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prpf40a NCBI NCBI:55660