2. Gene
  3. Tacstd2 - tumor-associated calcium signal transducer 2 Gene

Tacstd2 - tumor-associated calcium signal transducer 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ly97; EGP-1; TROP2; GA733-1

Gene ID: 56753 | Gene type: protein coding

About Tacstd2

Summary

Involved in several processes, including negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cellular component organization; and negative regulation of substrate adhesion-dependent cell spreading. Acts upstream of or within positive regulation of stem cell differentiation; regulation of epithelial cell proliferation; and ureteric bud morphogenesis. Located in several cellular components, including basal plasma membrane; extracellular space; and lateral plasma membrane. Is expressed in alimentary system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in corneal dystrophy and gelatinous drop-like corneal dystrophy. Orthologous to human TACSTD2 (tumor associated calcium signal transducer 2). [provided by Alliance of Genome Resources, Apr 2022]

Tacstd2 Products(1)

mRNA Protein Name
NM_020047.3 NP_064431.2 tumor-associated calcium signal transducer 2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of branching involved in ureteric bud morphogenesis IDA
IDA: Inferred from direct assay
22194864 MGI
involved in negative regulation of cell motility IDA
IDA: Inferred from direct assay
22194864 MGI
involved in negative regulation of epithelial cell migration IDA
IDA: Inferred from direct assay
22194864 MGI
involved in negative regulation of ruffle assembly IDA
IDA: Inferred from direct assay
22194864 MGI
involved in negative regulation of stress fiber assembly IDA
IDA: Inferred from direct assay
22194864 MGI
involved in negative regulation of substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
22194864 MGI
acts upstream of or within positive regulation of stem cell differentiation IDA
IDA: Inferred from direct assay
23070813 MGI
involved in regulation of epithelial cell proliferation IEP
IEP: Inferred from expression pattern
22194864 MGI
involved in ureteric bud morphogenesis IEP
IEP: Inferred from expression pattern
22194864 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
22194864 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
23070813 MGI
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
22194864 MGI
located in membrane IDA
IDA: Inferred from direct assay
23070813 MGI
located in nucleus IDA
IDA: Inferred from direct assay
23070813 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
9462726 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor-associated calcium signal transducer 2

cell surface glycoprotein Trop-2

lymphocyte antigen 97

tunor-associated calcium signal transducer 2

Recombinant Tacstd2 Proteins

Cat. No. Product Name Accession Purity
HY-P71387 TROP-2 Protein, Mouse (246a.a, HEK293, His) Q8BGV3 (Q25-G270) ≥95%
HY-P74488 TROP-2 Protein, Mouse (HEK293, hFc) Q8BGV3 (Q25-Q270) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14152 TACSTD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tacstd2 NCBI NCBI:4070
Macaca fascicularis Tacstd2 NCBI NCBI:102127436
Rattus norvegicus Tacstd2 NCBI NCBI:494343
Macaca mulatta Tacstd2 NCBI NCBI:716334